International Cancer Conference Journal

, Volume 8, Issue 4, pp 181–184 | Cite as

Hair regrowth using a properly fitted scalp cooling cap during adjuvant chemotherapy for breast cancer

  • Atsushi FushimiEmail author
  • Noboru Shinozaki
  • Hiroshi Takeyama
Case report


Patients with breast cancer desire to avoid chemotherapy-induced alopecia because it induces mental stress during treatment. Scalp cooling can suppress chemotherapy-induced alopecia without increasing the risk of scalp metastasis; however, in certain cases, alopecia cannot be prevented. The use of properly fitted scalp cooling caps has not yet been explored in Asian patients. Here, we report a case of hair regrowth using a properly fitted scalp cooling cap during adjuvant chemotherapy for breast cancer. A 51-year-old Japanese woman who was recalled by screening mammography for grouped amorphous calcifications and architectural distortion visited our hospital. Preoperative diagnosis was cT2N0M0 cStage IIA. Sentinel lymph node biopsy revealed axillary metastasis; hence, left mastectomy and axillary lymph node resection were performed. Pathological diagnosis revealed ER/PgR-positive and HER2-negative invasive lobular carcinoma (pT3N2M0 pStage IIIA). Adjuvant chemotherapy comprising four cycles of docetaxel every 3 weeks as well as four cycles of FEC every 3 weeks was performed with scalp cooling. After the first cycle of docetaxel, a 10-cm oval hair loss patch was observed at the vertex of the patient’s head. Assuming the scalp cooling cap was not efficiently in contact with the vertex of the patient’s head, we modified and properly fit the scalp cooling cap. After the third cycle of docetaxel, hair regrowth at the vertex began and gradually increased during chemotherapy. The patient did not require hair wigs during and after adjuvant chemotherapy. The scalp cooling cap should be carefully fitted at the vertex of the head, which is difficult to be covered, particularly in the case of Japanese patients. In addition, further development of properly fitted scalp cooling caps suitable for various individuals is necessary.


Breast cancer Scalp cooling cap Hair regrowth Adjuvant chemotherapy Alopecia 



We thank the staff of the chemotherapy room of Shin-yurigaoka General Hospital for their extraordinary support in this report. We would like to thank Century Medical Co. (Tokyo, Japan) for lending the Paxman scalp cooling system.

Compliance with ethical standards

Conflict of interest

The authors were lent the Paxman scalp cooling system for free from Century Medical Co. The authors have no financial relationship to Century Medical Co. or Paxman USA. These companies are not involved in this report. The authors declare that they have no other conflict of interest.

Ethical approval

For this type of study, formal consent is not required.

Informed consent

Informed consent was obtained from the patient included in the report.


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Copyright information

© The Japan Society of Clinical Oncology 2019

Authors and Affiliations

  1. 1.Department of Breast SurgeryShin-yurigaoka General HospitalKawasakiJapan
  2. 2.Department of SurgeryThe Jikei University School of MedicineTokyoJapan

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