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International Cancer Conference Journal

, Volume 8, Issue 4, pp 149–152 | Cite as

A case of leptomeningeal carcinomatosis in advanced gastric adenocarcinoma with controlled peritoneal dissemination

  • Mikihiro KanoEmail author
  • Jun Hihara
  • Naoki Hirabayashi
  • Taijiro Sueda
Case report
  • 12 Downloads

Abstract

A 48-year-old man with unresectable gastric cancer and widespread peritoneal dissemination received concentrated ascites reinfusion therapy, followed by systemic chemotherapy. However, leptomeningeal carcinomatosis (LMC) was diagnosed 1 year later. Spinal drainage and ventriculoperitoneal shunting improved the patient’s neurological functions for approximately 2 weeks. The patient died 2 months after LMC diagnosis, but these treatments temporarily improved the quality of life during end-of-life care.

Keywords

Advanced gastric cancer Leptomeningeal carcinomatosis Ventriculoperitoneal shunting 

Notes

Acknowledgements

We sincerely appreciate the carefully considered feedback and valuable comments provided by our staff. We thank Editage (www.editage.jp) for English-language editing.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Ethical standards

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions.

References

  1. 1.
    Nashimoto A, Akazawa K, Isobe Y et al (2013) Gastric cancer treated in 2002 in Japan: 2009 annual report of the JGCA nationwide registry. Gastric Cancer 16:1–27CrossRefGoogle Scholar
  2. 2.
    Kim NH, Kim JH, Chin HM et al (2014) Leptomeningeal carcinomatosis from gastric cancer: single institute retrospective analysis of nine cases. Ann Surg Treat Res 86:16–21CrossRefGoogle Scholar
  3. 3.
    Wasserstrom WR, Glass JP, Posner JB (1982) Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients. Cancer 49:759–772CrossRefGoogle Scholar
  4. 4.
    Kokkoris CP (1983) Leptomeningeal carcinomatosis: How does cancer reach the pia-arachnoid? Cancer 51:154–160CrossRefGoogle Scholar
  5. 5.
    Oh SY, Lee SJ, Lee J et al (2009) Gastric leptomeningeal carcinomatosis: multi-center retrospective analysis of 54 cases. World J Gastroenterol 15:5086–5090CrossRefGoogle Scholar
  6. 6.
    Lee JL, Kang YK, Kim TW et al (2004) Leptomeningeal carcinomatosis in gastric cancer. J Neurooncol 66:167–174CrossRefGoogle Scholar
  7. 7.
    Tomita H, Yasui H, Boku N et al (2012) Leptomeningeal carcinomatosis associated with gastric cancer. Int J Clin Oncol 17:361–366CrossRefGoogle Scholar
  8. 8.
    Boogerd W, van den Bent MJ, Koehler PJ et al (2004) The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomized study. Eur J Cancer 40:2726–2733CrossRefGoogle Scholar
  9. 9.
    Omuro AM, Lallana EC, Bilsky MH et al (2005) Ventriculoperitoneal shunt in patients with leptomeningeal metastasis. Neurology 64(9):1625–1627CrossRefGoogle Scholar

Copyright information

© The Japan Society of Clinical Oncology 2019

Authors and Affiliations

  1. 1.Department of SurgeryHiroshima City Asa Citizens HospitalHiroshimaJapan
  2. 2.Department of Surgery, Graduate School of Biomedical and Health SciencesHiroshima UniversityHiroshimaJapan

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