Inpatient Management of Autoimmune Blistering Diseases: an Update, Review, and Practical Guide

  • Anne L. MaranoEmail author
  • Adela R. Cardones
  • Russell P. HallIII
Hospital- based Dermatology (L Guggina and A Zhou, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Hospital-based Dermatology


Purpose of Review

Review the evaluation, management, and treatment of hospitalized autoimmune blistering diseases (AIBD) patients based on the current literature and expert opinion.

Recent Findings

The cost and prevalence of hospitalization for AIBD patients are increasing in the USA. Many factors associated with hospitalization of AIBD patients are related to patient access to dermatology care. Infections are a major cause for hospital admission among AIBD patients. The use of rituximab, especially early in the disease course, has transformed the outcomes among patients with pemphigus.


After reading this review, dermatologists should be more familiar with the inpatient AIBD clinical evaluation, including the medical history, physical examination, and laboratory work-up; the management of complications of AIBD and therapy; and the treatment ladder for selecting a steroid-sparing therapy for AIBD patients.


Autoimmune blistering disease Pemphigus Pemphigoid Inpatient dermatology 


Compliance with Ethical Standards

Conflict of Interest

Dr. Russell Hall III was on the Data Safety Monitoring Board for Roche-Genentech. He also received grants and was a consultant for the following entities: Principia, Syntimmune, Cabelletta Inc., and the National Institutes of Health.

Anne Marano performed an industry sponsored clinical trial at Viela Bio for cutaneous lupus.

Adela Cardones declares no conflicts of interest.

Human and Animal Rights

All reported studies/experiments with human or animal subjects performed by the authors have been previously published and compiled with all applicable ethical standards (including the Helsinki declaration and its amendments, institutional/national research committee standards, and international/national/institutional guidelines).


Papers of particular interest, published recently, have been highlighted as: • Of importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Anne L. Marano
    • 1
    Email author
  • Adela R. Cardones
    • 2
    • 3
  • Russell P. HallIII
    • 2
  1. 1.Department of DermatologyDuke University Medical CenterDurhamUSA
  2. 2.Department of DermatologyDuke University Medical CenterDurhamUSA
  3. 3.Durham VA Medical Center, Department of Medicine, Section of DermatologyDurhamUSA

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