A new method to identify fetal sex and trisomy 21 from the amniocentesis of pregnant women
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There are several methods to identify the sex of fetuses:
Imaging identification with B-mode ultrasound : after 15 weeks of gestation, ordinary B-mode ultrasound, three-dimensional color ultrasound, or four-dimensional color ultrasound can identify the sex of fetuses because at that time, there is obvious difference in the reproductive organ development between male and female fetuses. This method is time-window-restricted and requires skillful operator.
Microscopic karyotype identification method : the amniotic fluid in the uterus of pregnant women was obtained by amniocentesis technology, and fetal cells were isolated from the obtained amniotic fluid, cultured, and then the chromosome karyotype of fetal cells was analyzed. The sex chromosomes of the fetus were observed under the microscope to identify the sex type of fetuses. This method lasts 10 days, requires skillful operator and is labor intensive.
This study was supported by Scientific Research Program of Sichuan Health Commission of China (No. 16PJ404) and the Foundation of Sichuan Nursing Vocation College of China (No. 2017ZRZ04).
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Conflict of interest
We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work. There is no professional or other personal interest of any nature or kind in any product, service, and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled, “A new method to identify fetal sex and trisomy 21 from the amniocentesis of pregnant women”.
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