Duration of type 2 diabetes mellitus and pulmonary function tests: a correlative study
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Diabetes mellitus (DM) encompasses a group of metabolic disorders characterized by elevated levels of plasma glucose leading to macro- and micro-vascular damages to target organs. According to IDF, India had 73 million population of diabetes in 2017, and this figure may rise to 134 million adults by 2045 International Diabetes Federation, 2017. Since the alveolar capillary network in the lung is a large micro-vascular unit, microangiopathy may be targeting lungs along with other organs.
To correlate pulmonary function tests with duration of type 2 diabetes mellitus.
The cross-sectional study was conducted on one hundred six patients of type 2 diabetes mellitus who met the inclusion and exclusion criteria. Diabetic cases were categorized on the basis of duration of disease. RMS Helios 401 computerized spirometer was used to assess pulmonary functions. Statistical tests employed include t test, ANOVA, and correlation coefficient analysis.
The mean duration of disease for patients with diabetes was 10.17 ± 5.16 year. There was a significant negative correlation between the parameters of lung function test (p value < 0.05) with duration of diabetes.
We found that pulmonary functions have inverse relationship with increase in duration of type 2 diabetes mellitus.
KeywordsDiabetes mellitus Pulmonary function test Forced vital capacity Forced expiratory volume in first second
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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