Biomass Conversion and Biorefinery

, Volume 8, Issue 3, pp 635–646 | Cite as

Experimental design and economic analysis of 5-hydroxymethylfurfural synthesis from fructose in acetone-water system using niobium phosphate as catalyst

  • Everton G. L. de Carvalho
  • Fábio de A. RodriguesEmail author
  • Robson S. Monteiro
  • Rogério M. Ribas
  • Márcio J. da Silva
Original Article


5-Hydroxymethylfurfural (HMF) production from fructose was studied by using niobium phosphate as solid acid catalyst. HMF selectivity was optimized in a water-acetone system and compared to a water system. The HMF optimal selectivity for process carried out in the water-acetone system was 62.94%. When the process was performed in water, the HMF selectivity achieved 55.73%. These results were used in a large-scale simulation and economic analysis of the two processes. The higher selectivity of system water-acetone affected the HMF minimum selling price (MSP). The MSP value was 2.21 USD/kg for process performed in water-acetone and 3.05 USD/kg for process in water. In the sensitivity analysis, we have found that in addition to process selectivity, the fructose cost was the most significant factor affecting HMF price.


5-Hydroxymethylfurfural Acetone Niobium phosphate Simulation Economics 



The authors are thankful to the financial support from Companhia Brasileira de Metalurgia e Mineração, CBMM.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Everton G. L. de Carvalho
    • 1
  • Fábio de A. Rodrigues
    • 1
    Email author
  • Robson S. Monteiro
    • 2
    • 3
  • Rogério M. Ribas
    • 2
  • Márcio J. da Silva
    • 1
  1. 1.Department of ChemistryFederal University of ViçosaViçosaBrazil
  2. 2.Companhia Brasileira de Metalurgia e Mineração (CBMM)AraxáBrazil
  3. 3.Catalysis Consultoria LtdaRio de JaneiroBrazil

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