Guest Editorial: Perspectives on HIV and other age-related neurological diseases
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Over half of people with HIV (PWH) in the United States are 50 years of age or older (Prevention, C.f.D.C.a 2018). Among new infections, 17% of PWH were over the age of 50 years in the US in 2016. In fact, today PWH on combination anti-retroviral therapy (cART) rarely die from complications of AIDS, but instead suffer from age-related complications including neurocognitive decline and neurodegeneration of underlying HIV-associated neurocognitive disorders (HAND). Despite the success of cART, the prevalence of HAND is not decreasing and appears to be more severe in aging PWH. This special issue features articles that highlight parallels or differences in HIV-associated neurodegeneration/neurocognitive impairments with other age-related CNS disorders. Among the featured articles, authors address overlap between Alzheimer’s disease (AD) and HAND and neurodegeneration and the challenges faced in the search for biomarkers specific for HIV-associated CNS dysfunction. The life...
KeywordsHIV CNS Aging HAND
- Prevention, C.f.D.C.a., Vol. 2019. (ed. D.o.H.A. Prevention) (CDC, Online; 2018)Google Scholar