Reference Parameters for Protein Hydrogen Exchange Rates
The analysis of many hydrogen exchange (HX) experiments depends on knowledge of exchange rates expected for the unstructured protein under the same conditions. We present here some minor adjustments to previously calibrated values and a stringent test of their accuracy.
KeywordsHydrogen exchange HDX HX MS
This work was supported by research grants from the NIH (GM031846), NSF (MCB1020649), and the G. Harold and Leila Y. Mathers Charitable Foundation.