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Net survival of patients with colorectal cancer: a comparison of two periods

  • Zdravko ŠtorEmail author
  • Rok Blagus
  • Alessandro Tropea
  • Antonio Biondi
Original Article
  • 8 Downloads

Abstract

Background

The purpose of our analysis was to compare the results of treatment in patients who underwent resection for colorectal carcinoma.

Methods

In the period from 1/1/1991 to 31/12/2000 1478 patients with colorectal carcinoma underwent potentially curative resection. We divided them into two 5-year period groups according to different treatment regimes. The 5-year net survival rate was estimated, where the net survival is the probability of survival derived solely from the cancer-specific hazard.

Results

In a 10-year period, we resected 1478 patients. The 5-year net survival rate for R0-resected patients with colon cancer increased from 76.3 to 85.2% between the periods 1991–1995 and 1995–2000. The 5-year net survival rate for R0-resected patients with rectal cancer also increased from 67.5 to 73% in the same period.

Conclusion

A comparison of the 5-year net survival rate for R0-resected patients with colorectal cancer increased in the last period from 1995 to 2000 compared with the period from 1991 to 1995. In multivariate analysis, early stage at diagnosis and adjuvant chemotherapy was both associated with better net survival after surgery with curative intent. The improvement of net survival is potentially the result of combination of better surgical and adjuvant therapy.

Keywords

Colorectal cancer 5-Year net survival rate Standard oncological treatment 

Notes

Funding

The work was not supported by any fund/grant.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Research involving human participants and/or animals

All procedures performed in studies involving animals were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all subjects.

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Copyright information

© Italian Society of Surgery (SIC) 2019

Authors and Affiliations

  • Zdravko Štor
    • 1
    Email author
  • Rok Blagus
    • 2
  • Alessandro Tropea
    • 3
  • Antonio Biondi
    • 4
  1. 1.Department of Abdominal SurgeryUniversity Medical Centre LjubljanaLjubljanaSlovenia
  2. 2.Institute for Biostatistics and Medical Informatics, Medical FacultyUniversity of LjubljanaLjubljanaSlovenia
  3. 3.Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, IRCCS-ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione)University of Pittsburgh Medical Center ItalyPalermoItaly
  4. 4.Department of General Surgery and Medical Surgical SpecialtiesUniversity of CataniaCataniaItaly

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