Abstract
Fibrosing mediastinitis is a rare benign disorder caused by proliferation of acellular collagen and dense paucicellular fibrous tissue within the mediastinum. Its precise cause, pathogenesis and links to infectious (such as histoplasmosis or tuberculosis) and non-infectious (such as sclerosing cholangitis) diseases remain speculative. Affected patients present signs and symptoms related to obstruction of mediastinal hollow organs, such as large vessels, esophagus and airways. The present study reports the first case described in medical literature of medullar compression by a mediastinal mass penetrated into the spinal canal through neural foramens and causing claudication.
References
Rossi SE, McAdams HP, Rosado de Christenson ML et al (2001) Fibrosing medistianitis. Radiographics 21:737–757
Lima TC, Marchioni E, Capone D (2009) Fibrosing mediastinitis: a case report adiol. Bras 42(5):337–339
Comings DE, Skubi KB, Van Eyes J, Motulsky AG (1967) Familial multifocal fibrosclerosis. Findings suggesting that retroperitoneal fibrosis, mediastinal fibrosis, sclerosing cholangitis, Riedel’s thyroiditis, and pseudotumor of the orbit may be different manifestations of a single disease. Ann Inter Med 66:884–892
Sherrick AD, Brown LR, Harms GF et al (1994) The radiographic findings of fibrosing mediastinitis. Chest 106:484–489
Bays S, Rajakaruna C, Sheffield E, Morgan A (2004) Fibrosing medistinitis as a cause of superior vena cava syndrome. Eur J Cardiothorac Surg 26:453–455
Williams SM, Jones ET (1997) General case of the day. Fibrosing mediastinitis. Radiographics 17:1324–1327
Erasmus JJ, McAdams HP, Donnelly LF et al (2000) MR imaging of medistinal masses. Magn Reson Imaging Clin N Am 8:59–89
Ikeda K, Nomori H, Mori T et al (2007) Successful steroid treatment for fibrosing mediastinitis and sclerosing cervicitis. Ann Thorac Surg 83:1199–1201
Savelli BA, Parshley M, Morganroth ML (1997) Successful treatment of sclerosing cervicitis and fibrosing mediastinitis with tamoxifen. Chest 111:1137–1140
Greco P, Vaglio A, Manenti L et al (2004) Idiopathic retroperitoneal fibrosis. Giornale italiano di nefrologia 2:132–138
Kandzari DE, Warner JJ, O’Laughlin MP et al (2000) Percutaneous stenting of right pulmonary artery stenosis in fibrosing mediastinitis. Catheter Cardiovasc Interv 49:321–324
Doyle TP, Loyd JE, Robbins IM (2001) Percutaneous pulmonary artery and vein stenting: a novel treatment for mediastinal fibrosis. Am J Respir Crit Care Med 164:657–660
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Tancredi, A., Cuttitta, A., Del Naja, C. et al. Fibrosing mediastinitis as a cause of right claudication. Updates Surg 64, 63–67 (2012). https://doi.org/10.1007/s13304-011-0074-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13304-011-0074-7