Applied Nanoscience

, Volume 8, Issue 7, pp 1729–1741 | Cite as

Preparation, physicochemical properties and antimicrobial activity of η-modification of titanium(IV) oxide intercalated with poly(N-vinylcaprolactam)

  • Olesya I. TimaevaEmail author
  • Irina P. Chihacheva
  • Galina M. Kuzmicheva
  • Lidiya V. Saf’yanova
  • Ratibor G. Chumakov
  • Raisa P. Terekhova
Original Article


PVCL-intercalated samples containing nano-dimensional phases with η-modification of the TiO2−x·nH2O composition are obtained by hydrolysis of TiOSO4·xH2SO4·yH2O or TiOSO4·xH2O in the presence of poly(N-vinylcaprolactam) (PVCL). The incorporation of PVCL with water molecules into the interlayer space of the structure of the η-phase—TiO2−x·(PVCL nH2O)—is established by the X-ray diffraction study while the presence of PVCL in the sample composition is confirmed by the X-ray photoelectron and IR spectroscopy CHNS analysis and X-ray spectral microanalysis. Intercalated samples manifest the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans. It is shown that the sample composition (the content of hydrated titanium dioxide) the composition of the η-phase (the presence of PVCL and H2O or the water content in the interlayer space of the structure), and the surface composition (S in the form of SO42− groups O in the form of adsorbed water and OH groups) affect the antimicrobial activity in the dark.


Titanium(IV) oxide Intercalation Antimicrobial activity Nanoparticles Polymer 



This study was supported by the Ministry of Education and Science of the Russian Federation (agreement no. 4.1069.2017/PCh; 2017–2019).

Author contributions

The manuscript was written through contributions of all authors. All authors have given approval to the final version of the manuscript.

Compliance with ethical standards

Conflict of interest

The authors declare no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Federal State Budget Educational Institution of Higher Education “MIREA-Russian Technological University”MoscowRussia
  2. 2.Scientific Research Centre “Kurchatov Institute”MoscowRussia
  3. 3.Federal State Budget Enterprise “A.V. Vishnevsky Institute of Surgery” Ministry of Public Health of RussiaMoscowRussia

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