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Applied Nanoscience

, Volume 8, Issue 6, pp 1353–1360 | Cite as

Influence of solvents on the changes in structure, purity, and in vitro characteristics of green-synthesized ZnO nanoparticles from Costus igneus

  • G. Nandhini
  • R. Suriyaprabha
  • W. Maria Sheela Pauline
  • V. Rajendran
  • Wilhelm Karl Aicher
  • Oscar Komla Awitor
Original Article
  • 4 Downloads

Abstract

The present study is intended to produce high-purity zinc oxide nanoparticles from the leaves of Costus igneus and zinc acetate precursor via sustainable methods by the tribulation with three different solvents (hot water, methanol, and acetone) for the extraction of plant compounds. While examining the physico-chemical characteristics of ZnO nanoparticles incurred by the catalysis of plant bioactive compounds extracted from different solvents, the hot water extract-based green synthesis process yields higher purity (99.89%) and smaller particle size (94 nm) than other solvents. The optimization of the solvents used for the green synthesis of nanoparticles renders key identification in appropriate extraction of bioactive compounds suitable for the nucleation/production of nanoparticles in addition to annealing temperature. The impregnable usage of ZnO nanoparticles in clinical applications is further confirmed based on the treatment of particles (1–10 mg ml−1) against Gram-positive (S. aureus and S. epidermis) and Gram-negative bacteria (E. coli and K. pneumoniae) with respect to their growth inhibition. An in-force growth inhibition against particular S. aureus and S. epidermis imparted by the low concentration of ZnO nanoparticles signifies the utilization and consumption of green-synthesized high-purity nanoparticles for therapeutic and cosmetic applications.

Keywords

ZnO nanoparticles Green synthesis Costus igneus Solvent extraction In vitro 

Notes

Acknowledgements

Authors thank Department of Science and Technology (DST), New Delhi, and German Academic Exchange Service (DAAD), Germany, for the financial support under DST-DAAD project-based personal exchange programme (PPP) (F.No.INT/FRG/DAAD/P-13/2017 dt.28.08.2017). One of the authors (Dr. R. S) is also thankful to the University Grants Commission (UGC), New Delhi for the award of Postdoctoral Fellowship for Women (F.15-1/2015-17/PDFWM-2015-17-TAM-36274 dt.12/10/2015) to carry out this research work.

Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Centre for Nano Science and TechnologyK. S. Rangasamy College of TechnologyTiruchengodeIndia
  2. 2.Dr. N.G.P. Arts and Science CollegeCoimbatoreIndia
  3. 3.Department of UrologyUniversity of Tübingen HospitalTübingenGermany
  4. 4.Université Clermont Auvergne, CNRS/IN2P3, LPC+Clermont-FerrandFrance

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