Journal of Food Science and Technology

, Volume 56, Issue 11, pp 4757–4774 | Cite as

The importance of antioxidants and place in today’s scientific and technological studies

  • Cuma Zehiroglu
  • Sevim Beyza Ozturk SarikayaEmail author
Review Article


Antioxidants have become scientifically interesting compounds due to their many benefits such as anti-aging and anti-inflammatory. Today, it is still used in many areas. In food technology, antioxidants are added to many foodstuffs in order to enrich the foods and eliminate the problems. Therefore, studies to determine the antioxidant activities of natural foods and their components are also continuing rapidly. Antioxidants have also been replaced in the encapsulation studies used for the preservation and stabilization of food components. Of course, preservation of foods is as important as their production. The latest packaging techniques for food preservation are edible films and coatings. The protective function of edible films and coatings can be improved by the addition of antioxidants. Unlike these, studies on plants and animals have been investigated in vivo in terms of how the antioxidant activity changes as a result of metabolic activities. The role of antioxidant enzymes in these studies is quite large. Many results have been found for the elimination of diseases by either in vivo or in vitro studies regarding antioxidants. Thus, the importance of antioxidants increased with the use in pharmacology, cosmetics and medicine. In this study, we tried to bring a current perspective to antioxidants played an active role in many fields by combining the technological applications and scientific studies of antioxidants. In order to further customize the issue, we have done this especially for the food and health field and we have tried to emphasize the importance of antioxidants in this way.


Antioxidants Food Health Science Technology 


Supplementary material

13197_2019_3952_MOESM1_ESM.docx (38 kb)
Supplementary material 1 (DOCX 37 kb)


  1. Abuajah CI, Ogbonna AC, Osuji CM (2015) Functional components and medicinal properties of food: a review. J Food Sci Technol 52:2522–2529Google Scholar
  2. Agati G, Azzarello E, Pollastri S, Tattini M (2012) Flavonoids as antioxidants in plants: location and functional significance. Plant Sci 196:67–76CrossRefPubMedPubMedCentralGoogle Scholar
  3. Akcan T (2013) Research of natural antıoxidant blended edıble fılms on meatballs type of meat products. Higher Engineering Thesis, Ege University Graduate School of Natural and Applied Sciences, İzmir, p 98Google Scholar
  4. Alarcon CL, Deicona A (2013) Evaluating the antioxidant capacity of natural products: a review on chemical and cellular-based assays. Anal Chim Acta 763:1–10CrossRefGoogle Scholar
  5. Alvarez-Jubete L, Wijngaard H, Arendt EK, Gallagher E (2010) Polyphenol composition and in vitro antioxidant activity of amaranth, quinoa buckwheat and wheat as affected by sprouting and baking. Food Chem 119:770–778CrossRefGoogle Scholar
  6. Alvarez-Parrilla E, De La Rosa LA, Legarreta P, Saenz L, Rodrigo-García J, González-Aguilar GA (2010) Daily consumption of apple, pear and orange juice differently affects plasma lipids and antioxidant capacity of smoking and non-smoking adults. Int J Food Sci Nutr 61:369–380CrossRefPubMedPubMedCentralGoogle Scholar
  7. Attia AMM, Ibrahim FAA, Nabil GM, Aziz SW (2013) Antioxidant effects of ginger (Zingiber officinale Roscoe) against lead acetate-induced hepatotoxicity in rats. Afr J Pharm Pharmacol 7:1213–1219CrossRefGoogle Scholar
  8. Bahadoran Z, Golzarand M, Mirmiran P, Shiva N, Azizi F (2012) Dietary total antioxidant capacity and the occurrence of metabolic syndrome and its components after a 3-year follow-up in adults: Tehran Lipid and Glucose Study. Nutr Metab 9:1–9CrossRefGoogle Scholar
  9. Baycın D, Altıok E, Ulku S, Bayraktar O (2007) Adsorption of olive leaf (olea europaea l.) antioxidants on silk fibroin. J Agric Food Chem 55:1227–1236CrossRefPubMedPubMedCentralGoogle Scholar
  10. Beevi SS, Narasu ML, Gowda BB (2010) Polyphenolics profile, antioxidant and radical scavenging activity of leaves and stem of Raphanus sativus L. Plant Foods Hum Nutr 65:8–17CrossRefGoogle Scholar
  11. Biji KB, Ravishankar CN, Mohan CO, Srinivasa Gopal TK (2015) Smart packaging systems for food applications: a review. J Food Sci Technol 52:6125–6135CrossRefPubMedPubMedCentralGoogle Scholar
  12. Bulca S (2014) The composition of black cumin and use of black cumin and other essential oils as antioxidant in food technology. Adnan Menderes Univ Fac Agric J 11:29–36Google Scholar
  13. Butnariu M, Caunii A (2013) Design management of functional foods for quality of life improvement. Ann Agric Environ Med 4:736–741Google Scholar
  14. Cakmakcı S, Gundogdu E, Dagdemir E, Erdogan U (2014) Investigation of the possible use of black cumin (Nigella sativa L.) essential oil on butter stability. Kafkas Univ J Fac Vet Med 20:533–539Google Scholar
  15. Can A, Ozcelik B, Gunes G (2005) Antioxidant capacities of fruits and vegetables. In: GAP IV agricultural congress proceedings, pp 1458–1461Google Scholar
  16. Caple F, Williams EA, Spiers A, Tyson J, Burtle B, Daly AK, Mathers JC, Hesketh JE (2010) Inter-individual variation in DNA damage and base excision repair in young, healthy non-smokers: effects of dietary supplementation and genotype. Br J Nutr 103:1585–1593CrossRefGoogle Scholar
  17. Carocho M, Ferreira ICFR (2013) A review on antioxidants, prooxidants and related controversy: natural and synthetic compounds, screening and analysis methodologies and future perspectives. Food Chem Toxicol 51:15–25CrossRefGoogle Scholar
  18. Cavalcanti RN, Santos DT, Meireles MAA (2011) Non-thermal stabilization mechanisms of anthocyanins in model and food systems An overview. Food Res Int 44:499–509CrossRefGoogle Scholar
  19. Chaieb N, González JL, López-Mesas M, Bouslama M, Valiente M (2011) Polyphenols content and antioxidant capacity of thirteen faba bean (Vicia faba L.) genotypes cultivated in Tunisia. Food Res Int 44:970–977CrossRefGoogle Scholar
  20. Coruhli T (2013) Encapsulatıon of black mulberry anthocyanıns by ıonıc gellatıon method and optımızatıon of encapsulatıon paramaters by response surface methodology. Higher Engineering Thesis, Istanbul Technical University Institute of Science and Technology, İstanbulGoogle Scholar
  21. Demircan E (2016) Encapsulatıon of phenolıc compounds whıch extracted from apple peels. Higher Engineering Thesis, Istanbul Technical University Institute of Science and Technology, İstanbulGoogle Scholar
  22. Diaz-Garcia MC, Obon JM, Castellar MR, Collado J, Alacid M (2013) Quantification by UHPLC of total individual polyphenols in fruit juices. Food Chem 138:938–949CrossRefGoogle Scholar
  23. Diler A, Genc IY (2013) The usage of ısparta rose as food additive in seafoods: general evaluation in terms of antimicrobiological and antioxidant properties. Suleyman Demirel Univ J Inst Sci Technol 17:4–6Google Scholar
  24. Dogmus D, Durucasu I (2013) Antıoxıdant actıvıty of phenolıc components from n-butanol fractıon of flaxseed varıetıes. CBU J Sci 9(1):47–56Google Scholar
  25. Duan XJ, Zhang WW, Li XM, Wang BG (2006) Evaluation of antioxidant property of extract and fractions obtained from a red alga, Polysiphonia urceolata. Food Chem 95:37–43CrossRefGoogle Scholar
  26. El-Abed N, Kaabi B, Smaali MI, Chabbouh M, Habibi K, Mejri M, Nejib M, Ahmed SBH (2014) Chemical composition, antioxidant and antimicrobial activities of Thymus capitata essential oil with ıts preservative effect against listeria monocytogenes ınoculated in minced beef meat. Evid Based Complement Altern Med 42:1–11CrossRefGoogle Scholar
  27. Ellinger S, Müller N, Stehle P, Ulrich-Merzenich G (2011) Consumption of green tea or green tea products: ıs there an evidence for antioxidant effects from controlled interventional studies? Phytomedicine 18:903–915CrossRefGoogle Scholar
  28. Erkan N, Bilen G (2010) Effects of essential oils treatment on the frozen storage stability of chub mackerel fillets. J Consum Prot Food Saf 5:101–110CrossRefGoogle Scholar
  29. Fuchs-Tarlovsky V (2013) Role of antioxidants in cancer therapy. Nutrition 29:15–21CrossRefGoogle Scholar
  30. Galland L (2013) Functional foods: health effects and clinical applications A2. In: Caballero B (ed) Encyclopedia of human nutrition. Academic Press, Waltham, pp 366–371CrossRefGoogle Scholar
  31. Gao JJ, Zhang L, Qin AG, Yu XC (2008) Relative expression of SOD and CAT mRNA and activities of SOD and CAT in grafted cucumber leaves under NaCl stress. J Appl Ecol 19:1754–1758Google Scholar
  32. Ghasemnezhad M, Sherafati M, Payvast GA (2011) Variation in phenolic compounds, ascorbic acid and antioxidant activity of five coloured bell pepper (Capsicum annum) fruits at two different harvest times. J Funct Foods 3:44–49CrossRefGoogle Scholar
  33. Gokmen S, Palamutoglu R, Sarıcoban C (2012) Applications of encapsulation in food ındusty. Electr J Food Technol 1:36–50Google Scholar
  34. Gomez-Estaca J, Lopez-de-Dicastillo C, Hernandez-Munoz P, Catala R, Gavara R (2014) Advances in antioxidant active food packaging. Trends Food Sci Technol 35:42–51CrossRefGoogle Scholar
  35. Gulcin I (2012) Antioxidant activity of food constituents: an overview. Arch Toxicol 86:345–391CrossRefPubMedPubMedCentralGoogle Scholar
  36. He R, Ju X, Yuan J, Wang L, Girgih AT, Aluko RE (2012) Antioxidant activities of rapeseed peptides produced by solid state fermentation. Food Res Int 49:432–438CrossRefGoogle Scholar
  37. Heidebach T, Först P, Kulozik U (2012) Microencapsulation of probiotic cells for food applications. Crit Rev Food Sci Nutr 52:291–311CrossRefPubMedPubMedCentralGoogle Scholar
  38. Ignat I, Volf I, Popa V (2011) A critical review of methods for characterisation of polyphenolic compounds in fruits and vegetables. Food Chem 126:1821–1835CrossRefPubMedPubMedCentralGoogle Scholar
  39. Jakobek L (2015) Interactions of polyphenols with carbohydrates. Lipids Proteins Food Chem 175:556–567PubMedPubMedCentralGoogle Scholar
  40. Janes ME, Kooshesh S, Johnson MG (2002) Control of Listeria monocytogenes on the surface of refrigerated, ready-to-eat chicken coated with edible zein film coatings containing nisin and/or calcium propionate. J Food Sci 67:2754–2757CrossRefGoogle Scholar
  41. Johnston JE, Sepe HA, Miano CL, Brannan R, Alderton AL (2005) Honey inhibits lipid oxidation in ready-to-eat ground beef patties. Meat Sci 70:627–663CrossRefGoogle Scholar
  42. Karagoz Z, Candogan K (2007) Antimicrobial packaging in meat technology. Food 32:113–122Google Scholar
  43. Khanam UHS, Oba S, Yanase E, Murakami Y (2012) Phenolic acids, flavonoids and total antioxidant capacity of selected leafy vegetables. J Funct Foods 4:979–987CrossRefGoogle Scholar
  44. Kodal B (2008) Effects of antıoxıdant edıble fılms on oxıdatıve stabılıty of ground beef. Higher Engineering Thesis, Ankara University Institute of Science and Technology, p 81Google Scholar
  45. Koksal E, Bursal E, Dikici E, Tozoglu F, Gulcin I (2011) Antioxidant activity of Melissa officinalis leaves. J Med Plants Res 5:217–222Google Scholar
  46. Leopoldini M, Russo N, Toscano M (2011) The molecular basis of working mechanism of natural polyphenolic antioxidants. Food Chem 125:288–306CrossRefGoogle Scholar
  47. Lu TM, Lee CC, Mau JL, Lin SD (2010) Quality and antioxidant property of green tea sponge cake. Food Chem 119:1090–1095CrossRefGoogle Scholar
  48. McGhie TK, Walton MC (2007) Review: the bioavailability and absorption of anthocyanins: towards a better understanding. Mol Nutr Food Res 51:702–713CrossRefGoogle Scholar
  49. Muanda FN, Soulimani R, Diop B, Dicko A (2011) Study on chemical composition and biological activities of essential oil and extracts from stevia rebaudiana bertoni leaves. Food Sci Technol 44:1865–1872Google Scholar
  50. Munin A, Edwards-Lévy F (2011) Encapsulation of natural polyphenolic compounds; a review. Pharmaceutics 3:793CrossRefPubMedPubMedCentralGoogle Scholar
  51. Mut-Salud N, Álvarez PJ, Garrido JM, Carrasco E, Aránega A, Rodríguez-Serrano F (2016) Antioxidant ıntake and antitumor therapy: toward nutritional recommendations for optimal results. Oxid Med Cell Longev 2016:6719534CrossRefGoogle Scholar
  52. Naufalin R, Rukmini HS (2014) natural nanoencapsulant antioxidants based on kecombrang fruit. Int Conf Nutr Food Sci 71:118Google Scholar
  53. Nimse SB, Pal D (2015) Free radicals, natural antioxidants, and their reaction mechanisms. RSC Adv 5:27986–28006CrossRefGoogle Scholar
  54. Noviendri D (2014) Microencapsulation of fucoxanthin by water-in-oil-inwater (w/o/w) double emulsion solvent evaporation method. Squalen Bull Mar Fish Postharvest Biotechnol 9:137–150CrossRefGoogle Scholar
  55. Ou S, Wang Y, Tang S, Huang C, Jackson MG (2005) Role of ferulic acid in preparing edible films from soy protein isolate. J Food Eng 70:205–210CrossRefGoogle Scholar
  56. Pahlevi YW, Estiasih T, Saparianti E (2008) Microencapsulation of carotene extracts from neurospora sp. spores with protein based encapsulant using spray drying method. Jurnal Teknologi Pertanian 9:31–39Google Scholar
  57. Peh HY, Tan WSD, Liao W, Wong WSF (2016) Vitamin E therapy beyond cancer: tocopherol versus tocotrienol. Pharmacol Ther 162:152–169CrossRefGoogle Scholar
  58. Pham-Huy LA, He H, Pham-Huy C (2008) Free radicals, antioxidants in disease and health. Int J Biomed Sci 4:89–96PubMedPubMedCentralGoogle Scholar
  59. Podsedek A (2007) Natural antioxidants and antioxidant capacity of Brassica vegetables: a review. LWT 40:1–11CrossRefGoogle Scholar
  60. Quintavalla S, Vicini L (2002) Antimicrobial food packaging in meat industry. Meat Sci 62:373–380CrossRefGoogle Scholar
  61. Rajamani K, Manivasagam T, Anantharaman P, Balasubramanian T, Somasundaram ST (2011) Chemopreventive effect of Padina boergesenii extractson ferric nitrilotriacetate (Fe-NTA)-induced oxidativedamage in Wistar rats. J Appl Physiol 23:257–263Google Scholar
  62. Ratnam DV, Ankola DD, Bhardwaj V, Sahana DK, Kumar MNV (2006) Review role of antioxidants in prophylaxis and therapy: a pharmaceutical perspective. J Controll Release 113:189–207CrossRefGoogle Scholar
  63. Reddy CVK, Sreeramulu D, Raghunath M (2010) Antioxidant activity of fresh and dry fruits commonly consumed in India. Food Res Int 43:285–288CrossRefGoogle Scholar
  64. Ricci I, Artacho R, Olalla M (2010) Milk protein peptides with angiotensin Iconverting enzyme inhibitory (ACEI) activity. Crit Rev Food Sci Nutr 50:390–402CrossRefGoogle Scholar
  65. Sarmadi BH, Ismail A (2010) Antioxidative peptides from food proteins: a review. Peptides 31:1949–1956CrossRefGoogle Scholar
  66. Sevgi K, Tepe B, Sarikurkcu (2015) Antioxidant and DNA damage protection potentials of selected phenolic acids. Food Chem Toxicol 77:12–21CrossRefGoogle Scholar
  67. Shahidi F, Zhong Y (2010) Novel antioxidants in food quality preservation and health promotion. Eur J Lipid Sci Technol 112:930–940CrossRefGoogle Scholar
  68. Shebis Y, Iluz D, Kinel-Tahan Y, Dubinsky Z, Yehoshua Y (2013) Natural antioxidants: function and sources. Food Nutr Sci 4:643–649Google Scholar
  69. Singh M, Kaur M, Silakari O (2014) Flavones: an important scaffold for medicinal chemistry. Eur J Med Chem 84:206–239CrossRefGoogle Scholar
  70. Tekeogul H, Turan G, Kilinc B (2011) Production of non-stuffed bread with lentils (lemna minor). In: 16th national fisheries symposium, Antalya, p 274Google Scholar
  71. Tomaino A, Cimino F, Zimbalatti V, Venuti V, Sulfaro V, De Pasquale A, Saija A (2005) Influence of heating on antioxidant activity and the chemical composition of some spice essential oils. Food Chem 89:549–554CrossRefGoogle Scholar
  72. Turan G, Tekogul H, Kilinc B, Cirik S (2011) Sensory evaluation and analysis of shelf life of mossy breads prepared with ıron tank culture marine marul (Ulva Rigida). In: 16th national aquaculture symposium, October, Antalya, p 275Google Scholar
  73. Vaibhav DA, Arunkumar W, Abhijit MP, Arvind S (2011) Antioxidants as an immunomodulator. İnt J Curr Pharm Res 1:8–10Google Scholar

Copyright information

© Association of Food Scientists & Technologists (India) 2019

Authors and Affiliations

  1. 1.Center Research Laboratory Application and Research CenterGumushane UniversityGumushaneTurkey
  2. 2.Department of Food Engineering, Faculty of Engineering and Natural SciencesGumushane UniversityGumushaneTurkey

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