A Rare Complication of Diffuse Malignant Peritoneal Mesothelioma: Spontaneous Ileal Perforation
Malignant mesothelioma is a rare type of malignancy involving the serosal lining of the pleura, pericardium, peritoneum, and tunica vaginalis. It has an incidence of three cases per million per year. It is characterized with poor prognosis. Although most cases arise from the pleura, peritoneum may be the site of origin in 30% . Diffuse malignant peritoneal mesothelioma (DMPM), which is more prevalent in fifth to sixth decades of life, constitutes 90% of mesothelioma involving peritoneum [2, 3]. The clinical picture of DMPM is not clear cut from other cases. Abdominal pain, ascites, abdominal fullness due to masses, or systemic symptoms including malaise, decreased appetite, and weight loss are the most common complaints .
Spontaneous perforation of the small intestine due to either direct invasion or metastasis from pleural mesothelioma and DMPM is quite rare in English written literature. We present a case of spontaneous ileal perforation due to direct invasion from...
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