Nuclear Medicine and Molecular Imaging

, Volume 52, Issue 5, pp 401–404 | Cite as

Fibrosing Mediastinitis: a Rare Cause of Unilateral Absent Lung Perfusion on a V/Q Scan

  • Alyssa R. Goldbach
  • Suzanne Pascarella
  • Simin DadpravararEmail author
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We report a case of a 29-year-old female with a history of asthma, post-partum ARDS, and pulmonary hypertension who presents with severe shortness of breath. The patient describes her shortness of breath as progressive over the past 10 years. Chest radiography and CT angiography of the thorax showed findings consistent with fibrosing mediastinitis with severe stenosis of the left main pulmonary artery. This resulted in appearance of unilateral absent left lung perfusion on quantitative Tc-99-MAA perfusion and Xe-133 ventilation (V/Q) scan.


Ventilation and perfusion scan Fibrosing mediastinitis CTPA Histoplasma Mediastinal fibrosis 


Compliance with Ethical Standards

Conflict of Interest

Alyssa Goldbach, Suzanne Pascarella, and Simin Dadpravar declare that they have no conflict of interest.

Ethical Statement

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Institutional review board of our institute approved this retrospective study, and the requirement to obtain informed consent was waived.


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Copyright information

© Korean Society of Nuclear Medicine 2018

Authors and Affiliations

  • Alyssa R. Goldbach
    • 1
  • Suzanne Pascarella
    • 2
  • Simin Dadpravarar
    • 1
    Email author
  1. 1.Division of Nuclear Medicine and Molecular Biology, Department of RadiologyTemple University HospitalPhiladelphiaUSA
  2. 2.Division of Breast Imaging, Department of RadiologyTemple University HospitalPhiladelphiaUSA

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