Comparative study of intestinal malrotation in infant, children, and adult in a tertiary care center in India
- 26 Downloads
Intestinal malrotation (IM) is an uncommon condition and has varied presentation in different age groups. The study was aimed to evaluate differences in the clinical presentation, diagnosis, treatment, and outcome of IM in infants, children, and adults.
Data were collected from records of 79 patients with IM. Based on the age of presentation, these patients were categorized into three age groups: infants (up to 1 year), children (1–18 years), and adults (> 18 years). Follow up data were analyzed during 8 to 16 year after corrective surgery.
The overall age of presentation ranged from 8 days to 60 years. Twenty-eight, 29, and 22 patients belonged to the infant, children, and adult groups, respectively. The classical presentation of IM (bilious vomiting) was significantly higher in the infant compared to the children and adult groups (100% vs. 62% vs. 9.8%; p < 0.001). All infants presented with acute symptoms. However, children and adults had subacute or chronic presentations, respectively. The incidence of volvulus was significantly higher in the infant group than other two groups, (100% vs. 41% vs. 10%; p < 0.001). Doppler ultrasound was highly accurate in infants (100%), whereas contrast-enhanced computed tomography (CECT) abdomen was found to be most useful in adults. Postoperative complications were more common in adults.
Intestinal malrotation can present in patients of any age group. An increased awareness about the atypical presentations of this condition among adults may reduce the time to accurate diagnosis of this disease.
KeywordsIntestinal obstruction Malrotation Volvulus
The authors acknowledge the contribution of Dr. Alok Ranjan, Assistant Professor, Department of Community and Family Medicine, AIIMS, Patna for statistical analysis.
Compliance with ethical standards
Conflict of interest
UA, RK, RNP, BK, SK, and VPS declare that they have no conflict of interest.
The authors declare that the study was performed in a manner conforming to the Helsinki declaration of 1975, as revised in 2000 and 2008 concerning human and animal rights, and the authors followed the policy concerning informed consent as shown on Springer.com.
Written informed consent was obtained from all the patients for participation in this study.
The authors are solely responsible for the data and the content of the paper. In no way the Honorary Editor-in-Chief, Editorial Board Members, or the printer/publishers are responsible for the results/findings and content of this article.
- 11.Husberg B, Salehi K, Peters T, et al. Congenital intestinal malrotation in adolescent and adult patients: a 12-year clinical and radiological survey. Springerplus. 2016;5:245.Google Scholar
- 15.Devane SP, Coombes R, Smith VV, et al. Persistent gastrointestinal symptoms after correction of malrotation. Arch Dis Child. 1992;67:218–21.Google Scholar