Correlation Between Clinical Course and Biochemical Analysis in Odontogenic Space Infections
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To correlate the clinical course and biochemical analysis in odontogenic space infections.
A randomized prospective study was undertaken in 50 patients presenting with infections of odontogenic origin. The data were subjected to statistical analysis to co-relate the values of CRP, WBC count and ESR with the clinical course of odontogenic infections. The statistical analysis was carried out using SPSS Version 17.0 clinical parameters included pain, swelling, mouth opening, dyspnea, dysphagia, hoarseness, body temperature, active discharge, length of hospital stay and number of fascial spaces involved.
There was a significant correlation between all the clinical parameters and biochemical markers preoperatively as well as on various postoperative days.
According to the percentage rate of fall, CRP was considered as the best indicator of clinical course/recovery of the patient, followed by WBC count and ESR, respectively.
KeywordsOdontogenic infections Biomarkers WBC ESR CRP
The authors would like to thank late Dr. Sumeet Sandhu for her guidance and support in conducting the present study.
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical Approval for Research Involving Human Participants
All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all the individual participants included in the study.
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