Journal of Maxillofacial and Oral Surgery

, Volume 18, Issue 2, pp 203–209 | Cite as

Correlation Between Clinical Course and Biochemical Analysis in Odontogenic Space Infections

  • Amreen Kaur
  • Amneet SandhuEmail author
  • Tejinder Kaur
  • Ramandeep Singh Bhullar
  • Amit Dhawan
  • Jasmine Kaur
Clinical Paper



To correlate the clinical course and biochemical analysis in odontogenic space infections.


A randomized prospective study was undertaken in 50 patients presenting with infections of odontogenic origin. The data were subjected to statistical analysis to co-relate the values of CRP, WBC count and ESR with the clinical course of odontogenic infections. The statistical analysis was carried out using SPSS Version 17.0 clinical parameters included pain, swelling, mouth opening, dyspnea, dysphagia, hoarseness, body temperature, active discharge, length of hospital stay and number of fascial spaces involved.


There was a significant correlation between all the clinical parameters and biochemical markers preoperatively as well as on various postoperative days.


According to the percentage rate of fall, CRP was considered as the best indicator of clinical course/recovery of the patient, followed by WBC count and ESR, respectively.


Odontogenic infections Biomarkers WBC ESR CRP 



The authors would like to thank late Dr. Sumeet Sandhu for her guidance and support in conducting the present study.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval for Research Involving Human Participants

All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all the individual participants included in the study.


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Copyright information

© The Association of Oral and Maxillofacial Surgeons of India 2018

Authors and Affiliations

  • Amreen Kaur
    • 1
  • Amneet Sandhu
    • 1
    Email author
  • Tejinder Kaur
    • 1
  • Ramandeep Singh Bhullar
    • 1
  • Amit Dhawan
    • 1
  • Jasmine Kaur
    • 1
  1. 1.Department of Oral and Maxillofacial SurgerySri Guru Ram Das Institute of Dental Sciences and ResearchAmritsarIndia

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