Journal of Maxillofacial and Oral Surgery

, Volume 18, Issue 2, pp 256–259 | Cite as

Comparative Study Between Oral Lorazepam and Diazepam as Sedation in Oral and Maxillofacial Surgery

  • Vikas SharmaEmail author
  • Amaninder Singh
  • Parul Sharma
  • Simranjeet Kaur
  • Akanksha Zutshi
Original Article



The aim of the study was to compare the efficacy of oral lorazepam as night sedation and premedication with diazepam.


A prospective, randomized, and double-blind study was done in 50 healthy patients in each drug group. The impacted third molar impaction was taken as the study model. Study was carried out after giving bioequivalent doses of respective drugs for either side. All the patients were assessed for quality of sleep, sedation, recall of visual stimuli, cooperation shown by patient and recovery postoperatively.


The study concluded that lorazepam showed more advantages than diazepam as well as patient’s preference and satisfaction. However, postoperative recovery with lorazepam was longer than diazepam.


Lorazepam Diazepam Sedation Premedication 


Compliance with Ethical Standards

Conflict of interest

The authors declares that they have no conflict of interests.


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Copyright information

© The Association of Oral and Maxillofacial Surgeons of India 2018

Authors and Affiliations

  1. 1.Oral and Maxillofacial SurgeryNational Dental CollegeDerabassiIndia
  2. 2.Conservative and EndodonticsNational Dental College and HospitalDerabassiIndia
  3. 3.PanchkulaIndia

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