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Mean amplitude spectrum based epileptic state classification for seizure prediction using convolutional neural networks

  • Wenbin Hu
  • Jiuwen CaoEmail author
  • Xiaoping Lai
  • Junbiao Liu
Original Research
  • 18 Downloads

Abstract

An increasing number of algorithms have been proposed for epileptic seizure prediction in recent years. But most of them are based on a partition of the electroencephalograph (EEG) signal of an epileptic patient into preictal, ictal (seizure), and interictal states. In this paper, we propose to further divide the preictal interval into multiple subintervals. Besides discriminating the seizure state from the preictal and interictal states, we also distinguish the preictal subintervals from each other. An epileptic state classification algorithm for epileptic EEG signals is then developed. The amplitude spectrums of EEG signals from 18 channels are firstly calculated and divided into 19 frequency subbands. The mean amplitude spectrum (MAS) on each of the 19 frequency subbands is then computed for each channel to form a MAS map of size 18\(\times\)19. Finally, the MAS map is fed to a convolutional neural network (CNN) for feature extraction and a support vector machine (SVM) is employed for the epileptic state classification. Experiments show that, for a three-subinterval partition of the preictal state, a classification accuracy of 86.25% has been achieved on the CHB-MIT database by the MAS-based epileptic state classification algorithm using CNN and SVM.

Keywords

Seizure prediction Preictal state CNN Mean amplitude spectrum Support vector machine EEG 

Notes

Acknowledgements

This work was supported by the National Nature Science Foundation of China under Grant 61503104, and supported in part by the K. C. Wong Education Foundation and DAAD, the Zhejiang basic public welfare research program LGF18F010007, and the special fund project of information development in Shanghai: XX-XXFZ-02-18-2862.

Compliance with ethical standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Wenbin Hu
    • 1
  • Jiuwen Cao
    • 1
    • 2
    Email author
  • Xiaoping Lai
    • 1
  • Junbiao Liu
    • 2
  1. 1.Institute of Information and ControlHangzhou Dianzi UniversityHangzhouChina
  2. 2.Hangzhou Neuro Science and Technology Co. LtdHangzhouChina

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