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Waste and Biomass Valorization

, Volume 10, Issue 10, pp 2967–2973 | Cite as

Exploring the Chemical Composition and Anticancer Potential of Oil from Squid (Loligo duvauceli) Liver Waste from Fish Processing Industry

  • Meivelu MoovendhanEmail author
  • P. Seedevi
  • S. Vairamani
  • A. Shanmugam
Original Paper
  • 95 Downloads

Abstract

The present study was aimed to evaluate the nutritional fact and anticancer effect of liver oil extracted from the squid Loligo duvauceli. The ash and moisture content was noted as 3.21 and 2.13% whereas the total protein, lipid and carbohydrate, recorded 23.44, 21.23 and 2.13% respectively. The water and fat soluble vitamins and minerals were found in good level. The lipid profile was noted similarly to cod liver oil at the same time the good cholesterol was found in high level. Ten fatty acids were found especially DHA, EPA, omega-3 in high level. The essential amino acids were recorded at high level whereas Non-essential amino acids, moderate level. The anticancer ability of oil against lung cancer cell line (A549) showed better activity, up to 70% inhibition was noted at 960 µg/ml with the CTC50 of 260 µg/ml. In addition to this, there cytotoxicity effect was seen in Vero (normal) cell lines. The present study concludes that the L. duvauceli liver oil is a good source of nutrition and provides good health benefits to human.

Keywords

Proximate composition Lipid profile Amino acid Fatty acid profile Anticancer activity 

Notes

Acknowledgements

Authors are thankful to the Dean and Director, CAS in Marine Biology, Faculty of Marine Sciences, Annamalai University for providing all necessary facilities. The authors are also thankful to the Centre for Marine Living Resources and Ecology (CMLRE), Ministry of Earth Sciences, Kochi for the financial assistance.

Compliance with Ethical Standards

Conflict of interest

The authors declare no conflict of interest.

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© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Centre of Advanced Study in Marine Biology, Faculty of Marine SciencesAnnamalai UniversityParangipettaiIndia
  2. 2.Bioengineering and Drug Design Laboratory, Department of Biotechnology, Bhupat and Jyoti Mehta School of BiosciencesIndian Institute of Technology, Madras (IIT-M)ChennaiIndia
  3. 3.Department of Environmental SciencesPeriyar UniversitySalemIndia

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