Opioid free anesthesia: is it too early to bid adieu?

  • Rohan Magoon
  • Arindam ChoudhuryEmail author


Conflicts of interest

None declared.

Editorial responsibility

This submission was handled by Dr. Hilary P. Grocott, Editor-in-Chief, Canadian Journal of Anesthesia.


  1. 1.
    Bakan M, Umutoglu T, Topuz U, et al. Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double-blinded study. Braz J Anesthesiol 2015; 65: 191-9.CrossRefGoogle Scholar
  2. 2.
    Rudd RA, Seth P, David F, Scholl L. Increases in drug and opioid-involved overdose deaths - United States, 2010-2015. MMWR Morb Mortal Wkly Rep 2016; 65: 1445-52.CrossRefGoogle Scholar
  3. 3.
    Tripathy S, Rath S, Agrawal S, et al. Opioid-free anesthesia for breast cancer surgery: an observational study. J Anaesthesiol Clin Pharmacol 2018; 34: 35-40.Google Scholar
  4. 4.
    Mulier JP, Wouters R, Dillemans B, Dekock D. A randomized controlled, double- blind trial evaluating the effect of opioid-free versus opioid general anaesthesia on postoperative pain and discomfort measured by the QoR-40. J Clin Anesth Pain Med 2018; 2: 1-6.Google Scholar
  5. 5.
    Wardhan R, Chelly J. Recent advances in acute pain management: understanding the mechanisms of acute pain, the prescription of opioids, and the role of multimodal pain therapy. F1000Res 2017; DOI:

Copyright information

© Canadian Anesthesiologists' Society 2019

Authors and Affiliations

  1. 1.All India Institute of Medical SciencesNew DelhiIndia

Personalised recommendations