Pain exposure physical therapy in complex regional pain syndrome: promising enough to warrant further investigation

  • J. Bart StaalEmail author
  • Frank P. Klomp
  • Maria W. G. Nijhuis-van der Sanden


Conflicts of interest

The study authors have no competing interests to disclose.

Editorial responsibility

This submission was handled by Dr. Hilary P. Grocott, Editor-in-Chief, Canadian Journal of Anesthesia.


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    Duong S, Bravo D, Todd KJ, et al. Treatment of complex regional pain syndrome: an updated systematic review and narrative synthesis. Can J Anesth 2018; DOI: Scholar
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    Barnhoorn KJ, van de Meent H, van Dongen RT, et al. Pain exposure physical therapy (PEPT) compared to conventional treatment in complex regional pain syndrome type 1: a randomised controlled trial. BMJ Open 2015; 5: e008283.CrossRefGoogle Scholar
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    Barnhoorn K, Staal JB, van Dongen RT, et al. Pain exposure physical therapy versus conventional treatment in complex regional pain syndrome type 1-a cost-effectiveness analysis alongside a randomized controlled trial. Clin Rehabil 2018; DOI: Scholar
  4. 4.
    den Hollander M, Goossens M, de Jong J, et al. Expose or protect? A randomized controlled trial of exposure in vivo vs pain-contingent treatment as usual in patients with complex regional pain syndrome type 1. Pain 2016; 157: 2318-29.CrossRefGoogle Scholar
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Copyright information

© Canadian Anesthesiologists' Society 2018

Authors and Affiliations

  1. 1.Radboud Institute for Health Sciences, IQ HealthcareRadboud University Medical CenterNijmegenThe Netherlands
  2. 2.Research Group Musculoskeletal RehabilitationHAN University of Applied SciencesNijmegenThe Netherlands
  3. 3.Department of Orthopaedics, Section Physical TherapyRadboud University Medical CenterNijmegenThe Netherlands
  4. 4.Department of RehabilitationRadboud University Medical CenterNijmegenThe Netherlands

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