Preoperative smoking cessation as part of surgical prehabilitation

  • Dong An
  • Farrah Ayob
  • Wesley Rajaleelan
  • Frances Chung
  • Jean WongEmail author

To the Editor,

There is a growing interest in multimodal prehabilitation programs prior to surgery. Several recent guidelines have recommended multimodal prehabilitation programs that include smoking cessation. While preoperative smoking cessation programs reduce perioperative complications and increase long-term abstinence,1 the impact of smoking cessation interventions as part of multimodal prehabilitation programs has not been described. As such, we performed a systematic review to summarize the literature on prehabilitation programs that have included smoking cessation.

A literature search was performed in April 2018 of Medline, Medline In-Process, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, PubMed-NOT-Medline, CINAHL, Web of Science, and Scopus. Studies that evaluated the effect of preoperative smoking cessation as part of surgical prehabilitation were included.

The literature search identified seven studies for inclusion...


Conflicts of interest

Jean Wong reports grants from the Ontario Ministry of Health and Long-Term Care, Anesthesia Patient Safety Foundation and Acacia Pharma outside of the submitted work. Frances Chung reports research support from the Ontario Ministry of Health and Long-Term Care, University Health Network Foundation, Acacia Pharma, Medtronics grants to institution, Up-to-date royalties, STOP-Bang proprietary to University Health Network. The other authors have no conflicts of interest to report.

Editorial responsibility

This submission was handled by Dr. Steven Backman, Associate Editor, Canadian Journal of Anesthesia.


Department of Anesthesia, Toronto Western Hospital, Toronto, ON, Canada.


  1. 1.
    Thomsen T, Villebro N, Moller AM. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev 2014; 3: CD002294.Google Scholar
  2. 2.
    Wong J, Abrishami A, Riazi S, et al. A perioperative smoking cessation intervention with varenicline, counseling, and fax referral to a telephone quitline versus a brief intervention: a randomized controlled trial. Anesth Analg 2017; 125: 571-9.CrossRefGoogle Scholar
  3. 3.
    Wong J, Raveendran R, Chuang J, et al. Utilizing patient e-learning in an intervention study on preoperative smoking cessation. Anesth Analg 2018; 126: 1646-53.CrossRefGoogle Scholar
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    Wong J, Abrishami A, Yang Y, et al. A perioperative smoking cessation intervention with varenicline: a double-blind, randomized, placebo-controlled trial. Anesthesiology 2012; 117: 755-64.CrossRefGoogle Scholar
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    Myles PS, Leslie K, Angliss M, Mezzavia P, Lee L. Effectiveness of bupropion as an aid to stopping smoking before elective surgery: a randomised controlled trial. Anaesthesia 2004; 59: 1053-8.CrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists' Society 2019

Authors and Affiliations

  1. 1.Department of Anesthesia, Toronto Western Hospital, University Health NetworkUniversity of TorontoTorontoCanada
  2. 2.Department of AnesthesiaWomen’s College HospitalTorontoCanada

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