Re-establishment of neuromuscular block by rocuronium after sugammadex administration

  • Joaquin Fabregat-López
  • Gloria Veiga-Ruiz
  • Nuria Dominguez-Serrano
  • Maria Rosario García-Martinez
Correspondence

Keywords

Remifentanil Rocuronium Etomidate Neuromuscular Block Adductor Pollicis 

Notes

Acknowledgments

The authors sincerely thank Professor Aaron F. Kopman, Weill Cornell Medical College, for his helpful assistance with manuscript revision and Dr. Lucas Mengibar Fuentes, vascular surgeon, for his collaboration in patient care.

Conflicts of interest

Gloria Veiga-Ruiz, Nuria Dominguez-Serrano, and Joaquin Fabregat-López have received speakers’ fees from MSD. No external funding and no competing interest declared.

References

  1. 1.
    Staals LM, Snoeck MM, Driessen JJ, et al. Reduced clearance of rocuronium and sugammadex in patients with severe to end-stage renal failure: a pharmacokinetic study. Br J Anaesth 2010; 104: 31-9.CrossRefGoogle Scholar
  2. 2.
    de Boer HD, Driessen JJ, van Egmond J, Booij LH. Non-steroidal neuromuscular blocking agents to re-establish paralysis after reversal of rocuronium-induced neuromuscular block with sugammadex. Can J Anesth 2008; 55: 124-5.CrossRefGoogle Scholar
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    Cammu G, de Kam PJ, De Graeve K, et al. Repeat dosing of rocuronium 1.2 mg kg-1 after reversal of neuromuscular block by sugammadex 4.0 mg kg-1 in anaesthetized healthy volunteers: a modelling-based pilot study. Br J Anaesth 2010; 105: 487-92.CrossRefGoogle Scholar
  4. 4.
    Kopman AF. Managing neuromuscular block: where are the guidelines? Anesth Analg 2010; 111: 9-10.CrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists' Society 2011

Authors and Affiliations

  • Joaquin Fabregat-López
    • 1
  • Gloria Veiga-Ruiz
    • 1
  • Nuria Dominguez-Serrano
    • 1
  • Maria Rosario García-Martinez
    • 1
  1. 1.University Hospital Rosell CartagenaMurciaSpain

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