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Influence of pre-operative computerized tomography on the results of surgical treatment of secondary chondrosarcomas arising on osteochondromas: a retrospective sequential cohort study

  • Original Article
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European Orthopaedics and Traumatology

Abstract

Purpose

Computerized tomography (CT) is routinely used for diagnosis of secondary chondrosarcomas arising on osteochondromas but its actual influence on the surgical treatment is unknown. We hypothesized that pre-operative CT helped to lower the incidence of death, local recurrence, and post-operative complications after surgical treatment of secondary chondrosarcomas.

Methods

We conducted a single center retrospective analysis on a cohort of patients treated before and after systematic utilization of pre-operative CT. We included 26 cases of secondary chondrosarcoma arising on osteochondromas (21 cases of multiple exostoses and 5 cases of a solitary exostosis) among 24 patients (10 females and 14 males, mean age of 34.5 years) at a mean follow-up of 12 years. Fourteen cases were operated on before and 12 after beginning systematic utilization of CT. We compared the two groups with a Student’s t test regarding the rates of death, recurrence, and post-operative complications.

Results

We reported a lower rate of death and recurrences in the group with pre-operative CT, but the differences were not statistically significant.

Conclusion

Despite the retrospective design and the low number of patients in this study, systematic pre-operative CT helped to improve the results of the surgical treatment of secondary chondrosarcomas arising on osteochondromas.

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Acknowledgments

The authors would like to thank Dr Francis Y. Lee MD PhD and Ryan M. Coyle MS from Columbia University (New York, United States) for their help improving the quality of this research and the writing of the manuscript.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical standards statement

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery and Traumatology, Cochin Teaching Hospital, Assistance Publique-Hôpitaux de Paris AP-HP, University Paris Descartes, 27 rue du Faubourg Saint Jacques, 75014, Paris, France

    Jean-Charles Aurégan, Valérie Dumaine, Antoine Babinet, Bernard Tomeno, Philippe Anract & Frédéric Sailhan

  2. Department of Pathology, Cochin Teaching Hospital, Assistance Publique-Hôpitaux de Paris AP-HP, University Paris Descartes, 27 rue du Faubourg Saint Jacques, 75014, Paris, France

    Frédérique Larousserie

Authors
  1. Jean-Charles Aurégan
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  2. Frédérique Larousserie
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  3. Valérie Dumaine
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  4. Antoine Babinet
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  5. Bernard Tomeno
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  6. Philippe Anract
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  7. Frédéric Sailhan
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Correspondence to Jean-Charles Aurégan.

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Aurégan, JC., Larousserie, F., Dumaine, V. et al. Influence of pre-operative computerized tomography on the results of surgical treatment of secondary chondrosarcomas arising on osteochondromas: a retrospective sequential cohort study. Eur Orthop Traumatol 6, 45–50 (2015). https://doi.org/10.1007/s12570-014-0284-9

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  • DOI: https://doi.org/10.1007/s12570-014-0284-9

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