Biophysical Reviews

, Volume 9, Issue 6, pp 895–917 | Cite as

Plasma treatments of dressings for wound healing: a review

  • Nithya EswaramoorthyEmail author
  • David R. McKenzie


This review covers the use of plasma technology relevant to the preparation of dressings for wound healing. The current state of knowledge of plasma treatments that have potential to provide enhanced functional surfaces for rapid and effective healing is summarized. Dressings that are specialized to the needs of individual cases of chronic wounds such as diabetic ulcers are a special focus. A summary of the biology of wound healing and a discussion of the various types of plasmas that are suitable for the customizing of wound dressings are given. Plasma treatment allows the surface energy and air permeability of the dressing to be controlled, to ensure optimum interaction with the wound. Plasmas also provide control over the surface chemistry and in cases where the plasma creates energetic ion bombardment, activation with long-lived radicals that can bind therapeutic molecules covalently to the surface of the dressing. Therapeutic innovations enabled by plasma treatment include the attachment of microRNA or antimicrobial peptides. Bioactive molecules that promote subsequent cell adhesion and proliferation can also be bound, leading to the recruitment of cells to the dressing that may be stem cells or patient-derived cells. The presence of a communicating cell population expressing factors promotes healing.


Plasma treatments Surface modification Wound dressing Attachment and growth of cells Immobilization of biomolecules 


Compliance with ethical standards

Conflicts of interest

Nithya Eswaramoorthy declares that she has no conflicts of interest. David R. McKenzie declares that he has no conflicts of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by the author.


  1. Abidi N, Hequet E (2004) Cotton fabric graft copolymerization using microwave plasma. I. Universal attenuated Total reflectance-FTIR study. J Appl Polym Sci 93:145–154Google Scholar
  2. Agrawal P, Soni S, Mittal G, Bhatnagar A (2014) Role of polymeric biomaterials as wound healing agents. Int J Lower Extrem Wounds 13:180–190Google Scholar
  3. Anitha S, Vaideki K, Jayakumar S, Rajendran R (2015) Enhancement of antimicrobial efficacy of neem oil vapour treated cotton fabric by plasma pretreatment. Mater Technol Adv Perform Mater 30:368–377Google Scholar
  4. Annur D, Wang Z, Liao J, Kuo C (2015) Plasma-synthesized silver nanoparticles on electrospun chitosan nanofiber surfaces for antibacterial applications. Biomacromolecules 16:3248–3255PubMedGoogle Scholar
  5. Aukhil I (2000) Biology of wound healing. Periodontology 22:44–50Google Scholar
  6. Baek HS, Park YH, Ki CS, Park JC, Rah DK (2008) Enhanced chondrogenic responses of articular chondrocytes onto porous silk fibroin scaffolds treated with microwave-induced argon plasma. Surf Coat Technol 202:5794–5797Google Scholar
  7. Balaban N, Stoodley P, Fux CA, Wilson S, Costerton J, Dell'Acqua G (2005) Prevention of staphylococcal biofilm-associated infections by the quorum sensing inhibitor RIP. Clin Orthop Relat Res 437:48–54Google Scholar
  8. Balaban N et al (2007) Treatment of Staphylococcus Aureus biofilm infection by the quorum-sensing inhibitor R. Antimicrob Agents Chemother 51:2226–2229PubMedPubMedCentralGoogle Scholar
  9. Banerjee J, Sen CK (2015) microRNA and wound healing. Adv Exp Med Biol 888:291–305PubMedPubMedCentralGoogle Scholar
  10. Bax DV, McKenzie DR, Bilek MM, Weiss AS (2011a) Directed cell attachment by tropoelastin on masked plasma immersion ion implantation treated PTFE. Biomaterials 32:6710–6718PubMedGoogle Scholar
  11. Bax DV, Wang Y, Li Z, Maitz PKM, McKenzie DR, Bilek MM, Weiss AS (2011b) Binding of the cell adhesive protein tropoelastin to PTFE through plasma immersion ion implantation treatment. Biomaterials 32:5100–5111PubMedGoogle Scholar
  12. Bax DV et al (2012) Cell patterning via linker-free protein functionalization of an organic conducting polymer (polypyrrole) electrode. Acta Biomater 8:2538–2548PubMedGoogle Scholar
  13. Bhardwaj N, Kundu SC (2010) Electrospinning: a fascinating fiber fabrication technique. Biotechnol Adv 28:325–347PubMedGoogle Scholar
  14. Bilek MM, McKenzie DR (2010) Plasma modified surfaces for ovalent immobilization of functional biomolecules in the absence of chemical linkers: towards better biosensors and a new generation of medical implants. Biophys Rev 2:55–65PubMedPubMedCentralGoogle Scholar
  15. Bilek MM et al (2011) Free radical functionalization of surfaces to prevent adverse responses to biomedical devices. Proc Natl Acad Sci U S A 108:14405–14410PubMedPubMedCentralGoogle Scholar
  16. Boateng JS, Matthews KH, Stevens HNE, Eccleston GM (2008) Wound healing dressings and drug delivery systems: a review. J Pharm Sci 97:2892–2923PubMedGoogle Scholar
  17. Bodas D, Khan-Malek D (2007) Hydrophilization and hydrophobic recovery of PDMS by oxygen plasma treatment- an SEM investigation. Sensors Actuators B 123:368–373Google Scholar
  18. Bogaerts A, Neyts E, Gijbels R, van der Mullen J (2002) Gas discharge plasmas and their applications. Spectrochim Acta B 57:609–658. CrossRefGoogle Scholar
  19. Breitwieser D et al (2013) In situ preparation of silver nanocomposites on cellulosic fibers – microwave vs. conventional heating. Carbohydr Polym 94:677–686PubMedGoogle Scholar
  20. Cai Z, Qiu Y (2006) The mechanism of air/oxygen/helium atmospheric plasma action on PVA. J Appl Polym Sci 99:2233–2237Google Scholar
  21. Canal C, Gaboriau F, Villeger S, Cvelbar U, Ricard A (2009) Studies on antibacterial dressings obtained by fluorinated post-discharge plasma. Int J Pharm 367:155–161PubMedGoogle Scholar
  22. Chaivan P, Pasaja N, Boonyawan D, Suanpoot P, Vilaithong T (2005) Low- temperature plasma treatment for hydrophobicity improvement of silk. Surf Coat Technol 193:356–360Google Scholar
  23. Chalekson C, Neumeister M, Jaynes J (2003) Treatment of infected wounds with the antimicrobial peptide D2A21. J Trauma Inj Infect Crit Care 54:770–774Google Scholar
  24. Chapman B (1980) Glow discharge processes: sputtering and plasma etching. Wiley, New YorkGoogle Scholar
  25. Chen J (1991) Free radicals of fibers treated with low temperature plasma. J Appl Polym Sci 42:2035–2037Google Scholar
  26. Chen J-P, Lee W-L (2008) Collagen-grafted temperature-responsive nonwoven fabric for wound dressing. Appl Surf Sci 255:412–415Google Scholar
  27. Chen JS et al (2001) Structural and mechanical properties of nitrogen ion implanted ultra high molecular weight polyethylene. Surf Coat Technol 138:33–38Google Scholar
  28. Chen J-P, Kuo C-Y, Lee W-L (2012) Thermo-responsive wound dressings by grafting chitosan and poly(N-isopropylacrylamide) to plasma-induced graft polymerization modified non-woven fabrics. Appl Surf Sci 262:95–101Google Scholar
  29. Cheon YW et al (2010) Enhanced Chondrogenic responses of human articular chondrocytes onto silk fibroin/wool Keratose scaffolds treated with microwave-induced argon plasma. Artif Organs 34:384–392PubMedGoogle Scholar
  30. Chevallier P et al (2001) Ammonia RF-plasma on PTFE surfaces: chemical characterization of the species created on the surface by vapour- phase chemical derivatization. J Phys Chem B 105:12490–12497Google Scholar
  31. Dastjerdi R, Montazer M (2010) A review on the application of inorganic nano-structured materials in the modification of textiles: focus on anti-microbial properties. Colloids Surf B 79:5–18Google Scholar
  32. De Geyter N, Morent R, Leys C (2006) Pentration of a dieelctric barrier discharge plasma into textile structures at medium pressure. Plasma Sources Sci Technol 15:78Google Scholar
  33. De Geyter N, Morent R, Leys C, Gengembre L, Payen E (2007) Treatment of polymer films with a dielectric barrier discharge in air, helium and argon at medium pressure. Surf Coat Technol 201:7066–7075Google Scholar
  34. de Jesus Martínez-Gómez A, Manolache SO, Young RA, Denes FS (2010) Surface functionalization and biomolecule immobilization using plasma-generated free radicals on polypropylene. Polym Bull 65:293–308Google Scholar
  35. Desmet T, Morent R, Geyter ND, Leys C, Schacht E, Dubruel P (2009) Nonthermal plasma technology as a versatileStrategy for polymeric biomaterials surface modification: a review. Biomacromolecules 10:2351–2378PubMedGoogle Scholar
  36. Dowling DP (2014) Surface processing using cold atmospheric pressure plasmas. In: Cameron D (ed) Comprehensive materials processing, vol 4. Elsevier, Oxford, pp 171–185. CrossRefGoogle Scholar
  37. Dreifke MB, Jayasuriya AA, Jayasuriya AC (2015) Current wound healing procedures and potential care. Mater Sci Eng C 48:651–662Google Scholar
  38. Duplantier AJ, van Hoek ML (2013) The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds. Front Immunol 4:1–14Google Scholar
  39. Durso DF (1978) Chemical modification of cellulose – a historical review. Modified Cellulosics. Academic, New YorkGoogle Scholar
  40. Duscher D, Barrera J, Wong VW, Maan ZN, Whittam AJ, Januszyk M, Gurtner GC (2016) Stem cells in wound healing: the future of regenerative medicine? A mini-review. Gerontology 62:216–225PubMedGoogle Scholar
  41. Eddington DT, Puccinelli JP, Beebe DJ (2006) Thermal aging and reduced hydrophobic recovery of polydimethylsiloxane. Sensors Actuators B 114:170–172Google Scholar
  42. Encinas N, Díaz-Benito B, Abenojar J, Martínez MA (2010) Extreme durability of wettability changes on polyolefin surfaces by atmospheric pressure plasma torch. Surf Coat Technol 205:396–402. CrossRefGoogle Scholar
  43. Ershov S et al (2014) Free radical generation and concentration in a plasma polymer: the effect of aromaticity. ACS Appl Mater Interfaces 6:12395–12405. CrossRefPubMedGoogle Scholar
  44. Fahs F, Bi X, Yu F-S, Zhou L, Mi Q-S (2015) New insights into microRNAs in skin wound healing. IUBMB 67:889–896Google Scholar
  45. Fengel D, Wegener G (1984) Wood, chemistry, ultrastructure, reactions. Reactions in alkaline medium. Walter de Gruyter, BerlinGoogle Scholar
  46. Ferrerro F, Bongiovanni R (2006) Improving the surface properties of cellophane by air plasma treatment. Surf Coat Technol 200:4770–4776Google Scholar
  47. Freytag R, Donzé JJ (1983) Handbook of fiber science and technology: volume I. Chemical processing of fibers and fabrics, fundamentals and preparation, part a vol 1. Alkali treatment of cellulose fibres. Marcel Deckker, New YorkGoogle Scholar
  48. Goddard JM, Hotchkiss JH (2007) Polymer surface modification for the attachment of bioactive compounds. Prog Polym Sci 32:698–725Google Scholar
  49. Gomathi N, Sureshkumar A, Neogi S (2008) RF plasma treated polymers for biomedical applications. Curr Sci 94:1478–1486Google Scholar
  50. Govindarajan T, Shandas R (2014) A survey of surface modification techniques for next-generation shape memory polymer stent devices. Polymer 6:2309–2331Google Scholar
  51. Guimond S, Hanselmann B, Amberg M, Hegemann D (2010) Plasma functionalization of textiles: specifics and possibilities. Pure Appl Chem 82:1239–1245Google Scholar
  52. Guo S, DiPietro LA (2010) Factors affecting wound healing. J Dent Res 89:219–229PubMedPubMedCentralGoogle Scholar
  53. Gupta B, Agarwal R, Alam MS (2010) Textile based smart wound dressing. Indian J Fibers Text Res 35:174–187Google Scholar
  54. Guruvenketa S, Mohan Rao G, Komath M, Raichur AM (2004) Plasma surface modification of polystyrene and polyethylene. Appl Surf Sci 236:278–284Google Scholar
  55. Haddow DB, France RM, Short RD, MacNeil S, Dawson RA, Leggett GJ, Cooper E (1999) Comparison of proliferation and growth of human keratinocytes on plasma copolymers of acrylic acid/1,7-octadiene and self-assembled monolayers. J Biomed Mater Res 47:379–387PubMedGoogle Scholar
  56. Haddow DB, Steele DA, Short RD, Dawson RA, MacNeil S (2003) Plasma-polymerized surfaces for culture of human keratinocytes and transfer of cells to an in vitro wound-bed model. J Biomed Mater Res A 64:80–87PubMedGoogle Scholar
  57. Haddow DB, MacNeil S, Short RD (2006) A cell therapy for chronic wounds based upon a plasma polymer delivery surface. Plasma Process Polym 3:419–430Google Scholar
  58. He W, Ma Z, Yong T, Teo WE, Ramakrishna S (2005) Fabrication of collagen-coated biodegradable polymer nanofiber mesh and its potential for endothelial cells growth. Biomaterials 26:7606–7615PubMedGoogle Scholar
  59. He W, Yong T, Ma ZW, Inai R, Teo WE, Ramakrishna S (2006) Biodegradable polymer nanofiber mesh to maintain functions of endothelial cells. Tissue Eng 12:2457–2466PubMedGoogle Scholar
  60. Hochart F, De Jaeger R, Levalois-Grützmacher J (2003) Graft-polymerization of a hydrophobic monomer onto PAN textile by low-pressure plasma treatments. Surf Coat Technol 165:201–210Google Scholar
  61. Hocker H (2002) Plasma treatment of textile fibers. Pure Appl Chem 74:423–427Google Scholar
  62. Hodak SK, Supasai T, Paosawatyanyong B, Kamlangkla K, Pavarajarn V (2008) Enhancement of the hydrophobicity of silk fabrics by SF6 plasma. Appl Surf Sci 254:4744–4749Google Scholar
  63. Hossain MM, Hegemann D, Herrmann AS, Chabrecek P (2006) Contact angle determination on plasma-treated poly(ethylene terephthalate) fabrics and foils. J Appl Polym Sci 102:1452–1458Google Scholar
  64. Hu X, Liu S, Zhou G, Huang Y, Xie Z, Jing X (2014) Electrospinning of polymeric nanofibers for drug delivery applications. J Control Release 185:12–21PubMedGoogle Scholar
  65. Huang F, Wei Q, Wang X, Xu W (2006) Dynamic contact angles and morphology of PP fibres treated with plasma. Polym Test 25:22–27Google Scholar
  66. Hume EBH et al (2004) The control of staphylococcus epidermis biofilm formation and in vivo infection rates by covalently bound furanones. Biomaterials 25:5023–5030PubMedGoogle Scholar
  67. Hwang Y et al (2003) The effects of atmospheric pressure helium plasma treatment on adhesion and mechanical properties of aramid fibers. J Adhes Sci Technol 17:847–860Google Scholar
  68. Hwang YJ, Mccord MG, An JS, Kang BC, Park SW (2005) Effects of helium atmospheric pressure plasma treatment on low-stress mechanical properties of polypropylene nonwoven fabrics. Text Res J 75:771–778Google Scholar
  69. Inbakumar S, Morent R, De Geyter N, Desmet T, Anukaliani A, Dubruel P, Leys C (2010) Chemical and physical analysis of cotton fabrics plasma- treated with a low pressure glow discharge. Cellulose 17:417–426Google Scholar
  70. Jáuregui KMG, Cabrera JCC, Ceniceros EPS, Hernández JLM, Ilyina A (2009) A new formulated stable papain-pectin aerosol spray for skin wound healing. Biotechnol Bioprocess Eng 14:450–456Google Scholar
  71. Jeong L et al (2009) Plasma-treated silk fibroin nanofibers for skin regeneration. Int J Biol Macromol 44:222–228PubMedGoogle Scholar
  72. Kan C (2014) A novel green treatment for textiles: plasma treatment as a sustainable technology. CRC Press, New YorkGoogle Scholar
  73. Kan CW, Yuen CWM (2005) Effect of low temperature plasma treatment on wool fabric properties. Fibers Polym 6:169–173. CrossRefGoogle Scholar
  74. Kan CW, Chan K, Yuen CWM (2004) Surface characterization of low temperature plasma treated wool fiber. Fiber Polym 5:52–58Google Scholar
  75. Karahan HA, Özdogan E (2008) Improvements of surface functionality of cotton fibres by atmospheric plasma treatment. Fiber Polym 9:21–26Google Scholar
  76. Kasálková NS, Slepička P, Kolská Z, Sajdl P, Bačáková L, Rimpelová S, Švorčík V (2012) Cell adhesion and proliferation on polyethylene grafted with AU nanoparticles. Nucl Inst Methods Phys Res B 272:391–395Google Scholar
  77. Khan TA, Peh KK, Ch’ng HS (2000) Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing. J Pharm Pharm Sci 3:303–311PubMedGoogle Scholar
  78. Kiedrowski MR, Horswill AR (2011) New approaches for treating staphylococcal biofilm infections. Ann N Y Acad Sci 1241:104–121PubMedGoogle Scholar
  79. Koczulla A, Bals R (2003) Antimicrobial peptides: current status and theraputic. Potential Drugs 63:389–406PubMedGoogle Scholar
  80. Koh HS, Yong T, Chan CK, Ramakrishna S (2008) Enhancement of neurite outgrowth using nano-structured scaffolds coupled with laminin. Biomaterials 29:3574–3582PubMedGoogle Scholar
  81. Kosobrodova EA, Kondyurin AV, Fisher K, Moeller W, McKenzie DR, Bilek MMM (2012) Free radical kinetics in a plasma immersion ion implanted polystyrene: theory and experiment. Nucl Inst Methods Phys Res B 280:26–35Google Scholar
  82. Kosobrodova E, Jones RT, Kondyurin A, Chrzanowski W, Pigram PJ, McKenzie DR, Bilek MMM (2015) Orientation and conformation of anti-CD34 antibody immobilised on untreated and plasma treated polycarbonate. Acta Biomater 19:128–137PubMedGoogle Scholar
  83. Kwok DY, Neumann AW (1999) Contact angle measurement and contact angle interpretation. Adv Colloid Interf Sci 81:167–249. CrossRefGoogle Scholar
  84. Lai W-F, Siu PM (2014) MicroRNAs as regulators of cutaneous wound healing. J Biosci 39:519–524PubMedGoogle Scholar
  85. Lai J et al (2006) Study on hydrophilicity of polymer surfaces improved by plasma treatment. Appl Surf Sci 252:3375–3379. CrossRefGoogle Scholar
  86. Larsson A, D’erand H (2002) Stability of polycarbonate and polystyrene surfaces after Hydrophilization with high intensity oxygen RF plasma. J Colloid Interface Sci 246:214–221PubMedGoogle Scholar
  87. Lawton RA, Price CR, Runge AF, Doherty WJ, Saavedra SS (2005) Air plasma treatment of submicron thick PDMS polymer films: effect of oxidation time and storage conditions. Colloids Surf A Physicochem Eng Asp 253:213–215Google Scholar
  88. Le Y, Anand SC, Horrocks AR (1997) Recent developments in fibres and materials for wound management. Indian J Fibre Text Res 22:337–347Google Scholar
  89. Lewin M (1984) Handbook of fiber science and technology: chemical processing of fibers and fabrics, fundamentals and preparation, part B vol 1. Bleaching of cellulosic and synthetic fabrics. Marcel Deckker, New YorkGoogle Scholar
  90. Li S, Jinjin D (2007) Improvement of hydrophobic properties of silk and cotton by hexafluoropropene plasma treatment. Appl Surf Sci 253:5051–5055Google Scholar
  91. Luna SM, Silva SS, Gomes ME, Mano JF, Reis RL (2011) Cell adhesion and proliferation onto chitosan-based membranes treated by plasma surface modification. J Biomater Appl 26:101–116PubMedGoogle Scholar
  92. Machula H, Ensley B, Kellar R (2014) Electospun Tropoelastin for delivery of Theraputic adipose derived stem cells to full thickness dermal wounds. Adv Wound Care 3:367–375Google Scholar
  93. Madhyastha R, Madhyastha H, Nakajima Y, Omura S, Maruyama M (2012) MicroRNA signature in diabetic wound healing: promotive role of miR-21 in fibroblast migration. Int Wound J 9:355–361PubMedGoogle Scholar
  94. Maejima M (1983) Applying capillarity to estimation of space structure of fabrics. Text Res J 53:427–434Google Scholar
  95. Maver T, Hribernik S, Mohan T, Smrke DM, Maver U, Stana-Kleinschek K (2015) Functional wound dressing materials with highly tunable drug release properties. RSC Adv 5:77873–77884. CrossRefGoogle Scholar
  96. Mayet N, Choonara YE, Kumar P, Tomar LK, Tyagi C, Du Toit LC, Pillay V (2014) A comprehensive review of advanced biopolymeric wound healing systems. J Pharm Sci 103:2211–2230PubMedGoogle Scholar
  97. McCord MG, Hwang YJ, Qiu Y, Hughes LK, Bourham MA (2003) Surface analysis of cotton fabrics fluorinated in radio-frequency plasma. J Appl Polym Sci 88:2038–2047Google Scholar
  98. McCord MG, Hwang YJ, Qui Y, Hughes LK, Bourham MA (2003) Surface analysis of cotton fabrics fluorinated in radio frequency plasma. J Appl Polym Sci 88:2038–2047Google Scholar
  99. Mitchell SA, Davidson MR, Emmison N, Bradley RH (2004) Isopropyl alcohol plasma modification of polystyrene surfaces to influence cell attachment behaviour. Surf Sci 561:110–120Google Scholar
  100. Miwa M, Nakajima A, Fujishima A, Hashimoto K, Watanabe T (2000) Effects of the surface roughness on sliding angles of water droplets on Superhydrophobic surfaces. Langmuir 16:5754–5760Google Scholar
  101. Morent R, De Geyter N, Trentesaux M, Gengembre L, Dubruel P, Leys C, Payen E (2010) Influence of discharge atmosphere on the ageing behaviour of plasma-treated Polylactic acid. Plasma Chem Plasma Process 30:525–536Google Scholar
  102. Morent R, De Geyter N, Desmet T, Dubruel P, Leys C (2011) Plasma surface modification of biodegradable polymers: a review. Plasma Process Polym 8:171–190Google Scholar
  103. Nema SK, Jhala PB (2015) Plasma technologies for textile and apparel. WPI India, New DelhiGoogle Scholar
  104. Nithya E, Radhai R, Rajendran R, Shalini S, Rajendran V, Jayakumar S (2011) Synergetic effect of DC air plasma and cellulase enzyme treatment on the hydrophilicity of cotton fabrics. Carbohydr Polym 83:1652–1658Google Scholar
  105. Nithya E, Radhai R, Rajendran R, Jayakumar S, Vaideki K (2012) Enhancement of antimicrobial property of cotton fabric using plasma and enzyme pretreatments. Carbohydr Polym 88:986–991Google Scholar
  106. Nithya E, Radhai R, Prasanna S, Vaideki K, Rajendran R, Jayakumar S (2015) Physico-chemical analysis of oxygen plasma and enzyme treated cotton fabrics international journal of innovative research in science. Eng Technol 4:1333–1341Google Scholar
  107. Oehr C (2003) Plasma surface modification of polymers for biomedical use. Nucl Inst Methods Phys Res B 208:40–47Google Scholar
  108. Pane S, Tedesco R, Greger R (2001) Acrilic fabrics treated with plasma for outdoor application. J Ind Text 3:135–145Google Scholar
  109. Park K, Ju YM, Son JS, Ahn KD, Han DK (2007) Surface modification of biodegradable electrospun nanofiber scaffolds and their interaction with fibroblast. J Biomater Sci Polym Ed 18:369–382PubMedGoogle Scholar
  110. Parvizi J, Antoci V, Hickok NJ, Shapiro IM (2007) Selfprotective smart orthopedic implants. Exp Rev Med Devices 4:55–64Google Scholar
  111. Peršin Z, Devetak M, Drevenšek-Olenik I, Vesel A, Mozetič M, Stana-Kleinschek K (2013) The study of plasma's modifiation effects in viscose used ass an absorbent for wound -relevant fluids. Carbohydr Polym 97:143–151PubMedGoogle Scholar
  112. Peršin Z, Kleinschek KS, Mozetič M (2014a) The effects of storage gases on the durability of ammonia plasma effects with respect to wound fluid absorption and the biostatic activity of viscose non-wovens. Text Res J 84:751–763Google Scholar
  113. Peršin Z, Maver U, Pivec T, Maver T, Vesel A, Mozetič M, Stana-Kleinschek K (2014b) Novel cellulose based materialas for safe and efficient wound treatment. Carbohydr Polym 100:55–64PubMedGoogle Scholar
  114. Peršin Z, Zaplotnik R, Kleinschek KS (2014c) Ammonia plasma treated as a method promoting simultaneous hydrophilicity and antimicrobial activity of viscose wound dressing. Text Res J 84:140–156Google Scholar
  115. Perwuelz A, Casetta M, Caze C (2001) Liquid organisation during capillary rise in yarns—influence of yarn torsion. Polym Test 20:553–561Google Scholar
  116. Piraino F, Selimovic S (2015) A current view of functional biomaterials for wound care, molecular and cellular therapies. Biomed Res Int 2015:10. CrossRefGoogle Scholar
  117. Pivec T et al (2014) Modification of cellulose non-woven substrates for preparation of modern wound dressings. Text Res J 84:96–112Google Scholar
  118. Poll H, Schladitz U, Schreiter S (2001) Penetration of plasma effects into textile structures. Surf Coat Technol 142:489–493Google Scholar
  119. Powles RC, McKenzie DR, Meure SJ, Swain MV, James NL (2007) Nanoindentation response of PEEK modified by mesh-assisted plasma immersion ion implantation. Surf Coat Technol 201:7961–7969Google Scholar
  120. Qiu Y, Hwang Y, Zhang C, McCord M (2002) The effect of atmospheric pressure oxygen-helium plasma treatment on surface and mechanical properties of ultrahigh modulus polyethylene fiber. J Adhes Sci Technol 16:449–458Google Scholar
  121. Ren Y, Wang, C, Qiu, Yiping (2008) Aging of surface properties of ultra high modulus polyethylene fibers treatedwith He/O2 atmospheric pressure plasma jet.Surface Coatings Technol 202:2670–2676Google Scholar
  122. Řezníčkovác A, Kolská Z, Hnatowicz V, Stopka P, Švorčík V (2011) Comparison of glow argon plasma-induced surface changes of thermoplastic polymers. Nucl Inst Methods Phys Res B 269:83–88Google Scholar
  123. Rho KS et al (2006) Electrospinning of collagen nanofibers: effects on the behavior of normal human keratinocytes and early-stage wound healing. Biomaterials 27:1452–1461PubMedGoogle Scholar
  124. Rustad KC et al (2012) Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold. Biomaterials 33:80–90PubMedGoogle Scholar
  125. Sabharwal HS, Denes F, Nielsen L, Young RA (1993) Free-radical formation in jute from argon plasma treatment. J Agric Food Chem 41:2202–2207Google Scholar
  126. Samanta KK, Jassal M, Agrawal AK (2009) Improvement in water and oil absorbency of textile substrate by atmospheric pressure cold plasma treatment. Surf Coat Technol 203:1336–1342Google Scholar
  127. Saranwong N, Inthanon K, Wongkham W, Wanichapichart P, Suwannakachorn D, Yu LD (2012) Surface and protein analyses of normal human cell attachment on PIII-modified chitosan membranes. Nucl Inst Methods Phys Res B 272:386–390Google Scholar
  128. Schroder K, Meyer-Plath A, Keller D, Besch W, Babucke G, Ohl A (2001) Plasma- induced surface functionalization of polymeric biomaterials in ammonis plasma. Contrib Plasma Physics 41:562–572Google Scholar
  129. Sigurdsson S, Shishoo R (1997) Surface properties of polymers treated withTetrafluoromethane plasma. J Appl Polym Sci 66:1591–1601Google Scholar
  130. Silva SS, Luna SM, Gomes ME, Benesch J, Pashkuleva I, Mano JF, Reis RL (2008) Plasma surface modification of chitosan membranes: characterization and preliminary cell response studies. Macromol Biosci 8:568–576PubMedGoogle Scholar
  131. Siow KS, Britcher L, Kumar S, Griesser HJ (2006) Plasma methods for the generation of chemically reactive surfaces for biomolecule immobilization and cell colonization-a review. Plasma Process Polym 2:392–418Google Scholar
  132. Sun D, Stylios GK (2005) Investigating the plasma modification of natural fiber fabrics–the effect on fabric surface and mechanical properties. Text Res J 75:639–644Google Scholar
  133. Sun D, Stylios GK (2006) Fabric surface properties affected by low temperature plasma treatment. J Mater Process Technol 173:172–177Google Scholar
  134. Švorčík V et al (2009) Cytocompatibility of Ar+ plasma treated and au nanoparticle-grafted PE nuclear instruments and methods in physics. Res Sect B 267:1904–1910Google Scholar
  135. Tasker S, Badyal JPS, Backson SCE, Richards RW (1994) Hydroxyl accessibility in celluloses. Polym J 35:4717–4721Google Scholar
  136. Tran CTH, Craggs M, Smith LM, Stanley K, Kondyurin A, Bilek MM, McKenzie DR (2016) Covalent linker-free immobilization of conjugatable oligonucleotides on polypropylene surfaces. RSC Adv 6:83328–83336Google Scholar
  137. Tsafack MJ, Levalois-Grützmacher J (2007) Towards multifunctional surfaces using the plasma-induced graft-polymerization (PIGP) process: flame and waterproof cotton textiles. Surf Coat Technol 201:5789–5795Google Scholar
  138. Tseng H-J, Hsu S-h WM-W, Hsueh T-H, Tu P-C (2009) Nylon textiles grafted with chitosan by open air plasma and their antimicrobial effect. Fibers Polym 10:53–59Google Scholar
  139. Vaideki K, Jayakumar S, Rajendran R, Thilagavathi G (2008) Investigation on the effect of RF air plasma and neem leaf extract treatment on the surface modification and antimicrobial activity of cotton fabric. Appl Surf Sci 254:2472–2478. CrossRefGoogle Scholar
  140. Valenza A, Visco AM, Torrisi L, Campo N (2004) Characterization of ultra-high-molecular-weight polyethylene (UHMWPE) modified by ion implantation. Polymer 45:1707–1715Google Scholar
  141. Vigo TL (1994) Textile processing and properties: dyeing, finishing, and performance. Elsevier, AmsterdamGoogle Scholar
  142. Vohrer U, Muller M, Oehr C (1998) Glow discharge treatment for the modification of textiles. Surf Coat Technol 98:1128–1131Google Scholar
  143. Vosmanská V, Kolářová K, Rimpelová S, Kolská Z, Švorčík V (2015) Antibacterial wound dressing: plasma treatment effect on chitosan impregnation and in situ synthesis of silver chloride on cellulose surface. RSC Advances 5:17690–17699Google Scholar
  144. Wakida T, Takeda K, Tanaka I, Takagishi T (1989) Free radicals in cellulose fibres treated with low temperature plasma. Text Res J 59:49–53Google Scholar
  145. Wang Y, Zhao Y, Deng Y (2008) Effect of enzymatic treatment on cotton fiber dissolution in NaOH/urea solution at cold temperature. Carbohydr Polym 72:178–184Google Scholar
  146. Wang Q, Fan XR, Cui L, Wang P, Wu J, Chen J (2009) Plasma – aided cotton bioscouring: dielectric barrier discharge versus low pressure oxygen plasma. Plasma Chem Plasma Process 29:399–409Google Scholar
  147. Ward TL, Jung H, Hinojosa O, Benerito RR (1979) Characterization and use of radio frequency plasma-activated natural polymers. J Appl Polym Sci 23:1987–2003Google Scholar
  148. Wong K, Tao X, Yuen C, Yeung K (1999) Low temperature plasma treatment of linen. Text Res J 69:846–855Google Scholar
  149. Woodward I, Schofield W, Roucoules V, Badyal J (2003) Super-hydrophobic surfaces produced by plasma fluorination of polybutadiene films. Langmuir 19:3432–3438Google Scholar
  150. Yang S, Gupta M (2004) Surface modification of polyethyleneterephthalate by an atmospheric-pressure plasma source. Surf Coat Technol 187:172–176Google Scholar
  151. Yang L, Chen J, Guo Y, Zhang Z (2009) Surface modification of a biomedical polyethylene terephthalate (PET) by air plasma. Appl Surf Sci 255:4446–4451. CrossRefGoogle Scholar
  152. Yao C, Li X, Neoh KG, Shi Z, Kang ET (2008) Surface modification and antibacterial activity of electrospun polyurethane fibrous membranes with quaternary ammonium moieties. J Membr Sci 320:259–267Google Scholar
  153. Yin Y, Nosworthy N, Youssef H, Gong B, Bilek M, McKenzie D (2009) Acetylene plasma coated surfaces for covalent immobilization of proteins. Thin Solid Films 517:5343–5346Google Scholar
  154. Yip J, Chan K, Sin KM, Lau KS (2002) Low temperature plasma-treated nylon fabrics. J Mater Process Technol 123:5–12. CrossRefGoogle Scholar
  155. Yoo HS, Kim TG, Park TG (2009) Surface-functionalized electrospun nanofibers for tissue engineering and drug delivery. Adv Drug Deliv Rev 61:1033–1042PubMedGoogle Scholar
  156. Yoshida S, Hagiwara K, Hasebe T, Hotta A (2013) Surface modification of polymers by plasma treatments for the enhancement of biocompatibility and controlled drug release. Surf Coat Technol 233:99–107Google Scholar
  157. Young T (1805) Philos Trans R Soc Lond A 95:65–75Google Scholar
  158. Zahedi P, Rezaeian I, Ranaei-Siadat S-O, Jafari S-H, Supaphol P (2010) A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages. Polym Adv Technol 21:77–95Google Scholar
  159. Zhang W et al (2006) Plasma surface modification of poly vinyl chloride for improvement of antibacterial properties. Biomaterials 27:44–51PubMedGoogle Scholar
  160. Zhang W, Luo Y, Wang H, Jiang J, Pu S, Chu PK (2008) Ag and ag/N2 plasma modification of polyethylene for the enhancement of antibacterial properties and cell growth/proliferation. Acta Biomater 4:2028–2036PubMedGoogle Scholar
  161. Zhou Y, Yang D, Chen X, Xu Q, Lu F, Nie J (2008) Electrospun water-soluble Carboxyethyl chitosan/poly(vinyl alcohol) Nanofibrous membrane as potential wound dressing for skin regeneration. Biomacromolecules 9:349–354PubMedGoogle Scholar
  162. Zhu X, Chian KS, Chan‐Park MBE, Lee ST (2005) Effect of argon- plasma treatment on proliferation of human-skin derived fibroblast on chitosan membrane in vitro. J Biomed Mater Res A 73A:264–274Google Scholar
  163. Zille A, Oliveira FR, Souto AP (2015) Plasma treatment in textile industry. Plasma Process Polym 12:98–131Google Scholar

Copyright information

© International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.School of PhysicsThe University of SydneySydneyAustralia

Personalised recommendations