Cross-Family Comparative Proteomic Study and Molecular Phylogeny of MAP Kinases in Plants
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Mitogen-activated protein kinases are serine/threonine-specific protein kinases and they are closely related to cyclin-dependent kinases. They constitute functionally significant family of proteins that is involved in various cellular functions like response to mitogens, osmotic stress, heat shock and proinflammatory cytokines as well as known to play key role in proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. MAP kinases are characteristically found in eukaryotes only, though they are fairly diverse and encountered in all animals, fungi and plants, and even in an array of unicellular eukaryotes. In this study 24 MAP kinase sequences from various plant species were selected in order to compare their conserved regions, amino acid composition, evolutionary orders and other statistical parameters.
KeywordsMAP kinases Comparative genomics Molecular phylogeny
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