Adenovirus-associated hemophagocytic syndrome in a young child

  • Fei-Zhou Zhang
  • Yu-Qing Cai
  • Lan-Fang TangEmail author
Clinical Image



We thank the parents of the patient for permitting us to publish the detailed case information.

Author contributions

FZZ completed the first draft; YQC collated relevant literature and clinical data. LFT revised the manuscript to ensure the authenticity and practicability of the manuscript.


This study was partly supported by National Natural Science Foundation of China (81470214) and Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents (2016).

Compliance with ethical standards

Conflict of interest

There is no competing interest.


  1. 1.
    Henter J-I, Horne A, Aricó M, Egeler RM, Filipovich AH, Imashuku S, Ladisch S, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48:124–31.CrossRefPubMedGoogle Scholar
  2. 2.
    Censoplano N, Gorga S, Waldeck K, Stillwell T, Rabah-Hammad R, Flori H. Neonatal adenovirus infection complicated by hemophagocytic lymphohistiocytosis syndrome. Pediatrics. 2018;141(Suppl 5):S475–80.CrossRefPubMedGoogle Scholar

Copyright information

© Children's Hospital, Zhejiang University School of Medicine 2019

Authors and Affiliations

  1. 1.Department of Pulmonology, Children’s HospitalZhejiang University School of MedicineHangzhouChina

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