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Quantitative assessment of tricuspid regurgitation using right and left ventricular stroke volumes obtained from tomographic equilibrium radionuclide ventriculography

  • Damien Eyharts
  • Yoan Lavie-Badie
  • Stéphanie Cazalbou
  • Pauline Fournier
  • Eve Cariou
  • Pierre Pascal
  • Francisco Campelo-Parada
  • Bertrand Marcheix
  • Michel Galinier
  • Isabelle Berry
  • Didier Carrié
  • Olivier LairezEmail author
ORIGINAL ARTICLE

Abstract

Background

Quantitative assessment of valve regurgitation using volumetric method by comparing right and left ventricular stroke volumes is still under investigations.

Aims

To investigate the accuracy of tomographic equilibrium radionuclide ventriculography (t-ERV) for the quantification of tricuspid regurgitation (TR).

Methods and Results

Sixty-one patients (44 men; mean age 59 ± 12 years) who underwent both t-ERV and transthoracic echocardiography (TTE) studies within 2 weeks for right ventricular systolic function assessment were eligible for inclusion. A sub-group of 22 patients underwent both t-ERV and CMR. Patients with mitral/aortic regurgitation by TTE were excluded of the study. TR regurgitant volume (RVol) was calculated using the proximal isovelocity surface area (PISA) method from TTE and the volumetric method (right ventricular stroke volume minus left ventricular stroke volume) from t-ERV. There was a significant correlation between RVol as assess by ERV and by TTE (R = 0.95, P < 0.0001). Intraclass correlation coefficient between TTE and ERV for TR quantification was 0.95 (P < 0.0001). Among patients who underwent CMR, the correlation between RVol obtained by TTE and by t-ERV and CMR were R = 0.81 and R = 0.75, respectively (all P < 0.0001).

Conclusion

TR assessment using the t-ERV correlates well with PISA from TTE in patients referred for right ventricular systolic function assessment.

Keywords

Tricuspid regurgitation quantitative assessment radionuclide equilibrium ventriculography transthoracic echocardiography 

Abbreviations

ICC

Intraclass correlation coefficient

CMR

Cardiac magnetic resonance imaging

MR

Mitral regurgitation

PISA

Proximal isovelocity surface area

RVol

Regurgitant volume

TTE

Transthoracic echocardiography

TR

tricuspid regurgitation

t-ERV

Tomographic equilibrium radionuclide ventriculography

Notes

Disclosure

Damien Eyharts, Yoan Lavie-Badie, Stéphanie Cazalbou, Pauline Fournier, Eve Cariou, Pierre Pascal, Francisco Campelo-Parada, Bertrand Marcheix, Michel Galinier, Isabelle Berry, Didier Carrié, and Olivier Lairez have nothing to disclose.

Supplementary material

12350_2019_1781_MOESM1_ESM.pptx (18.7 mb)
Electronic supplementary material 1 (PPTX 19190 kb)

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Copyright information

© American Society of Nuclear Cardiology 2019

Authors and Affiliations

  • Damien Eyharts
    • 1
    • 2
    • 6
  • Yoan Lavie-Badie
    • 1
    • 2
    • 3
    • 6
  • Stéphanie Cazalbou
    • 1
    • 2
    • 6
  • Pauline Fournier
    • 1
    • 2
    • 6
  • Eve Cariou
    • 1
    • 2
    • 4
    • 6
  • Pierre Pascal
    • 2
    • 3
  • Francisco Campelo-Parada
    • 1
    • 6
  • Bertrand Marcheix
    • 4
    • 6
    • 7
  • Michel Galinier
    • 1
    • 2
    • 4
    • 6
  • Isabelle Berry
    • 2
    • 3
    • 4
  • Didier Carrié
    • 1
    • 2
    • 5
    • 6
  • Olivier Lairez
    • 1
    • 2
    • 3
    • 4
    • 6
    Email author
  1. 1.Department of CardiologyRangueil University HospitalToulouseFrance
  2. 2.Cardiac Imaging CenterToulouse University HospitalToulouseFrance
  3. 3.Department of Nuclear MedicineRangueil University HospitalToulouseFrance
  4. 4.Medical School of RangueilUniversity Paul SabatierToulouseFrance
  5. 5.Medical School of PurpanUniversity Paul SabatierToulouseFrance
  6. 6.Heart Valve CenterToulouse University HospitalToulouseFrance
  7. 7.Department of Cardiac SurgeryRangueil University HospitalToulouseFrance

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