Barry L. Zaret, MD and H. William Strauss, MD
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Open image in new windowOpen image in new window In the early 1970s, management of coronary artery disease (CAD) was changing rapidly. Favaloro performed the first successful coronary artery bypass surgery (CABG) in 1967.1 Over the next few years, CABG became the standard of care in selected patients with angina pectoris. However, selection of suitable surgical candidates required invasive coronary angiography. In 1971 and 1973, Zaret and Strauss reported two seminal clinical studies that were timely and relevant for clinical cardiology.2,3 They demonstrated that using conventional nuclear imaging resting left ventricular function and regional wall motion could be quantified and that myocardial perfusion could be visualized, at rest and after exercise for detection of scar and myocardial ischemia.
The promise of noninvasive evaluation of patients with suspected CAD foreshadowed the beginning of the field of clinical nuclear cardiology. Within a few years, myocardial perfusion imaging...
The Members of the History Corner: George Beller, MD (Acting Chair); James Udelson, MD; Frans J. Th. Wackers, MD, PhD; Ignasi Carrio, MD.
The author declares that he has no conflict of interest.