Cardiovascular disease in the literature: A selection of recent original research papers
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Long-Term Survival Following Multivessel Revascularization in Patients With Diabetes. The FREEDOM Follow-On Study. J Am Coll Cardiol2019; https://doi.org/10.1016/j.jacc.2018.11.001
Background: The FREEDOM trial showed that in patients with diabetes and multivessel CAD, CABG is associated with a reduction in major adverse cardiovascular and cerebrovascular events compared to PCI. Farkouh et al. from the University of Toronto, Canada reported on the long-term outcomes from FREEDOM.
Findings: Of the original 1900 patients in FREEDOM, long-term follow-up (7.5 years, interquartile range 5 to 9 years) was available on 943 (49.6%). Mortality at 8 years in the PCI group was 24.3% compared to 18.3% in CABG group (hazard ratio 1.36, 95% CI 1.07 to 1.74, P = .01). The survival benefit of CABG versus PCI was more evident in younger patients (≤ 63 year), in those that ever smoked, and in those from centers in North America.
Significance:In patients with diabetes and multivessel CAD and without...
Dr. Aljaroudi reports no conflicts of interest. Dr. Hage reports grant support from Astellas Pharma and GE Healthcare.