Cardiovascular disease in the literature: A selection of recent original research papers

  • Fadi G. HageEmail author
  • Wael AlJaroudi
Review of the Literature

Long-Term Survival Following Multivessel Revascularization in Patients With Diabetes. The FREEDOM Follow-On Study. J Am Coll Cardiol2019;

Background: The FREEDOM trial showed that in patients with diabetes and multivessel CAD, CABG is associated with a reduction in major adverse cardiovascular and cerebrovascular events compared to PCI. Farkouh et al. from the University of Toronto, Canada reported on the long-term outcomes from FREEDOM.

Findings: Of the original 1900 patients in FREEDOM, long-term follow-up (7.5 years, interquartile range 5 to 9 years) was available on 943 (49.6%). Mortality at 8 years in the PCI group was 24.3% compared to 18.3% in CABG group (hazard ratio 1.36, 95% CI 1.07 to 1.74, P = .01). The survival benefit of CABG versus PCI was more evident in younger patients (≤ 63 year), in those that ever smoked, and in those from centers in North America.

Significance:In patients with diabetes and multivessel CAD and without...



Dr. Aljaroudi reports no conflicts of interest. Dr. Hage reports grant support from Astellas Pharma and GE Healthcare.

Copyright information

© American Society of Nuclear Cardiology 2019

Authors and Affiliations

  1. 1.Division of Cardiovascular Disease, Department of MedicineUniversity of Alabama at BirminghamBirminghamUSA
  2. 2.Section of CardiologyBirmingham Veterans Affairs Medical CenterBirminghamUSA
  3. 3.Division of Cardiovascular MedicineClemenceau Medical CenterBeirutLebanon

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