Isolated cardiac amyloidosis. Utility of bone seeking tracers scintigraphy in differentiating the subtype of amyloid: A case report
Three types of amyloid are responsible for cardiac amyloidosis. Differentiation of the subtype is critical for the disease progression and the therapeutic decision.
Myocardial scintigraphy using Tc-PYP is able to differentiate the cardiac amyloid subtype with high sensitivity and specificity. The myocardial uptake of PYP is higher in patients with TTR amyloidosis.
Non-invasive tests for the detection of cardiac amyloidosis, like myocardial scintigraphy with bone seeking tracers, can play a major role in the diagnosis progression and therapeutic management of patients with cardiac amyloidosis.
KeywordsHeart failure SPECT 99mTc
Senile systemic amyloidosis
Light chain amyloidosis
Cardiac magnetic resonance imaging
Heart to contralateral
Hereditary transthyretin amyloidosis
O. Bourogianni, E. Papadaki, E. Foukarakis and S. Koukouraki as authors of this case report have nothing to declare.
- 7.Βois J, Chareonthaitawee P. Radionuclide imaging in congestive heart failure, assessment of viability, sarcoidosis, and amyloidosis. Cardiol Clin. 2015;34:119-32.Google Scholar