Journal of Nuclear Cardiology

, Volume 24, Issue 4, pp 1127–1129 | Cite as

Cardiovascular disease in the literature: A selection of recent original research papers

  • Fadi G. HageEmail author
  • Wael AlJaroudi
Review of the Literature

Comparison of the Efficacy and Safety of Early Rule-Out Pathways for Acute Myocardial Infarction. Circulation. 2017;135:1586-1596.

Background:Guidelines from the European Society of Cardiology (ESC) support early testing with high-sensitivity troponin in patients presenting with chest pain to the emergency department. Chapman et al. from the Royal Infirmary of Edinburgh, United Kingdom, compared two pathways that utilize high-sensitivity troponin: ESC pathway and the previously validated High-STEACS pathway. The ESC pathway rules out myocardial infarction (MI) when troponin is less than 95th percentile at presentation in those with symptoms >6 hours and at 3 hours in those with symptoms less than 6 hours or if it did not change from baseline. The High-STEACS pathway rules out MI when trop <5 ng/L in those with symptoms ≥2 hours. In patients with symptoms <2 hours or troponin ≥5 ng/L but less than 99th percentile, the test is repeated at 3 hours and MI is ruled out if trop is...



Dr. Hage reports research support from Astellas Pharma.

Copyright information

© American Society of Nuclear Cardiology 2017

Authors and Affiliations

  1. 1.Division of Cardiovascular Disease, Department of MedicineUniversity of Alabama at BirminghamBirminghamUSA
  2. 2.Section of CardiologyBirmingham Veterans Affairs Medical CenterBirminghamUSA
  3. 3.Division of Cardiovascular MedicineClemenceau Medical CenterBeirutLebanon

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