Usefulness of magnifying endoscopy and endoscopic ultrasonography for the gastric involvement of follicular lymphoma

  • Yudai KoyaEmail author
  • Tatsuyuki Watanabe
  • Keiichiro Kume
  • Shinsuke Kumei
  • Ichiro Yoshikawa
  • Takashi Tasaki
  • Masaru Harada
Case Report


A 61-year-old man received an esophagogastroduodenoscopy for further investigation of mesenteric lymphadenopathy. Esophagogastroduodenoscopy revealed swollen gastric folds and cobble stone mucosa in the gastric body. Magnifying endoscopy with narrow-band imaging showed branched abnormal vessels and the absence or destruction of gastric pits. Endoscopic ultrasonography (EUS) depicted homogeneously hypoechoic thickening of the submucosal layer where the mucosal changes were observed. The patient was diagnosed with follicular lymphoma by biopsy of these lesions. We should recognize that these endoscopic features are consistent with follicular lymphoma involving the stomach and that concurrent EUS is useful for diagnosis and identification of adequate biopsy sites.


Endoscopic ultrasonography Extranodal marginal-zone lymphoma of mucosal-associated lymphoid tissue Follicular lymphoma Magnifying endoscopy 


Compliance with ethical standards

Conflict of interest

Yudai Koya, Tatsuyuki Watanabe, Keiichiro Kume, Shinsuke Kumei, Ichiro Yoshikawa, Takashi Tasaki and Masaru Harada declare that they have no conflict of interest.

Human/animal rights

All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed consent

Informed consent was obtained from all patients for being included in the study.


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Copyright information

© Japanese Society of Gastroenterology 2019

Authors and Affiliations

  • Yudai Koya
    • 1
    Email author
  • Tatsuyuki Watanabe
    • 1
  • Keiichiro Kume
    • 1
  • Shinsuke Kumei
    • 1
  • Ichiro Yoshikawa
    • 1
  • Takashi Tasaki
    • 2
  • Masaru Harada
    • 1
  1. 1.The Third Department of Internal Medicine, School of MedicineUniversity of Occupational and Environmental HealthKitakyushuJapan
  2. 2.Department of PathologyUniversity of Occupational and Environmental HealthKitakyushuJapan

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