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The successful treatment of hepatocellular carcinoma arising from congenital hepatic fibrosis using radiofrequency ablation under laparoscopy

  • Takuya Hirosawa
  • Naoki Morimoto
  • Kouichi MiuraEmail author
  • Kohei Ono
  • Shunji Watanabe
  • Takeshi Fujieda
  • Kozue Murayama
  • Yoshinari Takaoka
  • Hiroaki Nomoto
  • Mamiko Tsukui
  • Norio Isoda
  • Toshiro Niki
  • Katsutoshi Tokushige
  • Hironori Yamamoto
Case Report
  • 39 Downloads

Abstract

Congenital hepatic fibrosis (CHF), a fibropolycystic disease, is characterized by bile duct malformation, periportal fibrosis, and renal polycystic disease. Although cholangiocellular carcinoma is the primary tumor arising from fibropolycystic diseases, hepatocellular carcinoma (HCC) is extremely rare. In addition, no algorism for determining the optimum HCC treatment has yet been available in cases of fibropolycystic disease due to variations in the background liver and renal conditions. We herein report a patient with HCC arising from CHF that was successfully treated using radiofrequency ablation (RFA) under laparoscopic assistance. A 37-year-old man with CHF was admitted to our hospital for treatment of HCC in 2014. Imaging revealed HCC located in hepatic segments II and VIII with diameters of 28 and 24 mm, respectively. There had been no histories of recurrent cholangitis or renal failure after when CHF was diagnosed in 2003. In addition, esophageal varices were well controlled. We achieved sufficient ablation using a bipolar ablation system without any complications. The post-operative course was uneventful, and the patient was free from HCC for 4 years. Thus, locoregional therapy, including RFA, is acceptable for the treatment of HCC arising from CHF when the background liver and kidney are preserved.

Keywords

Congenital hepatic fibrosis Hepatocellular carcinoma Locoregional therapy Radiofrequency ablation 

Notes

Compliance with ethical standards

Conflict of interest

All authors have nothing conflict of interests in this study.

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Copyright information

© Japanese Society of Gastroenterology 2019

Authors and Affiliations

  • Takuya Hirosawa
    • 1
  • Naoki Morimoto
    • 1
  • Kouichi Miura
    • 1
    Email author
  • Kohei Ono
    • 1
  • Shunji Watanabe
    • 1
  • Takeshi Fujieda
    • 1
  • Kozue Murayama
    • 1
  • Yoshinari Takaoka
    • 1
  • Hiroaki Nomoto
    • 1
  • Mamiko Tsukui
    • 1
  • Norio Isoda
    • 1
  • Toshiro Niki
    • 2
  • Katsutoshi Tokushige
    • 3
  • Hironori Yamamoto
    • 1
  1. 1.Division of Gastroenterology, Department of MedicineJichi Medical University School of MedicineShimotsukeJapan
  2. 2.Division of Integrative Pathology, Department of PathologyJichi Medical University School of MedicineShimotsukeJapan
  3. 3.Department of GastroenterologyTokyo Women’s Medical UniversityTokyoJapan

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