We read with interest the case report by Larson et al.  in the Journal of Hematopathology and would like to share a similarly challenging case of plasma cell leukemia encountered in a young patient at our center.
A 36-year-old lady presented with a history of backache and generalized weakness for 3 months. She had severe pallor; however, there was no localized bony tenderness, lymphadenopathy, or organomegaly. Investigations revealed hemoglobin 51 g/L (reference range 120–160 g/L), total leukocyte count 243 × 10
9/L (reference range 4–11 × 10
9/L), and platelets 119 × 10
9/L (reference range 150–400 × 10
9/L). A peripheral blood smear showed marked lymphocytosis with absolute lymphocyte count of 206.6 × 10
9/L (reference range 1.0–4.0 × 10
9/L) and 3% cells showing lymphoplasmacytic morphology (Fig.
1, left image). Biochemistry revealed normal renal function, albumin-corrected serum calcium (10.3 mg/dL, reference range 9–11 mg/dL), and elevated lactate dehydrogenase...
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The authors declare that they have no conflict of interest.
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