Primary Cutaneous Mucormycosis in a Beta-Thalassemia Patient

  • Mozhdeh SepaskhahEmail author
  • Iman Moezzi
  • Mohammad Ali Davarpanah
  • Fatemeh Sari Aslani

To the Editor,

Cutaneous Mucormycosis (CM) is among the known causes of morbidity and mortality in immunocompromised patients. The infection is caused by Zygomycetes, a member of the order of Mucorales. Cutaneous mucormycosis is the third most common form of this disease behind rhinocerebral and pulmonary forms [1].

Although mostly occurring in immunocompromised and diabetic patients, there are several reports of CM infection in the immunocompetent patients. The most common risk factor is breach in the skin barrier. Desferoxamine therapy is another risk factor for CM [1].

A 24-year-old woman, a known case of beta-thalassemia intermedia presented with a necrotic crusted ulcer on her chin a few days after blunt trauma. She received repeated monthly blood transfusion and Desferoxamine injection. She had history of splenectomy due to hematologic indication one month prior to skin lesion. She was febrile (temperature = 39 °C orally) on admission. There was necrotic ulcerative plaque on chin...


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Conflict of interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Indian Society of Hematology and Blood Transfusion 2018

Authors and Affiliations

  1. 1.Molecular Dermatology Research CenterShiraz University of Medical SciencesShirazIran
  2. 2.Department of Dermatology, Shahid Faghihi HospitalShiraz University of Medical SciencesShirazIran
  3. 3.HIV/AIDS Research CenterShiraz University of Medical SciencesShirazIran
  4. 4.Department of Pathology, Medical Sciences SchoolShiraz University of Medical SciencesShirazIran
  5. 5.Department of Internal MedicineNamazi Hospital, Namazi SquareShirazIran

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