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Thrombocytopenia in Infants: CMV-Related ITP or CMV-Related Thrombocytopenia?

  • Fatih Isleyen
  • Mehmet Tekin
  • Capan Konca
Correspondence
  • 36 Downloads

To the Editor,

Platelets are blood elements which take part in the first phase of hemostasis. Etiology of thrombocytopenia depends on deficient proliferation, distribution disorder or excess degradation. Excess degradation appears as idiopathic thrombocytopenic purpura (ITP) and viral infections [1]. While CMV-related hematologic problems are frequently seen in newborns and immune-compromised patients, they are rare in normal subjects [2]. While patients who developed thrombocytopenia are reported in literature, numbers of pediatric cases are small [3, 4, 5]. In this paper, we presented three infant cases that were considered to have ITP in the initial assessment, who were detected to have CMV and responded to IVIG treatment.

Case 1; An 11-months-old boy was admitted due to rash on the legs. The rash was started a day ago. Platelet count was 18.700/mm3. Peripheral blood smear examination was normal with regard to red blood cell (RBC) and WBC count; there were 1–2 platelets in every...

Notes

Compliance with Ethical Standards

Conflict of interest

All authors declare that they have no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

References

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    Plosa EJ, Esbenshade JC, Fuller MP, Weitkamp JH (2012) Cytomegalovirus infection. Pediatr Rev 33:156–163CrossRefGoogle Scholar
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    DiMaggio D, Anderson A, Bussel JB (2009) Cytomegalovirus can make immune thrombocytopenic purpura refractory. Br J Haematol 46:104–112CrossRefGoogle Scholar

Copyright information

© Indian Society of Hematology and Blood Transfusion 2018

Authors and Affiliations

  1. 1.Department of Pediatrics, School of MedicineAdiyaman UniversityAdiyamanTurkey

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