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Nano Research

, Volume 11, Issue 3, pp 1369–1378 | Cite as

Anomalous enhancement of fluorescence of carbon dots through lanthanum doping and potential application in intracellular imaging of ferric ion

  • Shenghong Yang
  • Xiaohan Sun
  • Zhaoyan Wang
  • Xiayan WangEmail author
  • Guangsheng Guo
  • Qiaosheng PuEmail author
Research Article

Abstract

An anomalous enhancement of fluorescence of carbon dots (CDs) was observed via lanthanum (La) doping. La-doped CDs (La-CDs) were prepared through microwave pyrolysis within 4 min. With La3+ doping, the emission band shifted from blue to green although La3+ is non-fluorescent. The quantum yield and fluorescence lifetime improved by about 20% and 35%, respectively. All experiment results indicate that La3+ doping is an effective way to tune fluorescence and improve the performance of CDs. Another unique attribute of La-CDs is high sensitivity to Fe3+. The La-CD-based fluorescence probe was established and used for sensitive and selective detection of Fe3+ with a limit of detection of 91 nmol/L. The proposed fluorescence probe also was successfully employed to visualize intracellular Fe3+ in live HeLa cells through cell imaging. It was also shown that yttrium exhibited the same fluorescence enhancement effect as La. The results may provide a new route for preparing CDs with special properties.

Keywords

rear earth doping carbon dots fluorescence tuning ferric ion cell imaging 

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Notes

Acknowledgements

The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China (Nos. 21375005, 21575054 and 21527808).

Supplementary material

12274_2017_1751_MOESM1_ESM.pdf (1.3 mb)
Anomalous enhancement of fluorescence of carbon dots through lanthanum doping and potential application in intracellular imaging of ferric ion

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Copyright information

© Tsinghua University Press and Springer-Verlag GmbH Germany 2018

Authors and Affiliations

  1. 1.State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, Department of ChemistryLanzhou UniversityLanzhouChina
  2. 2.School of pharmacyLanzhou UniversityLanzhouChina
  3. 3.Beijing Key Laboratory for Green Catalysis and Separation, Department of Chemistry and Chemical EngineeringBeijing University of TechnologyBeijingChina

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