Chirale Epoxidierung von Aryl-Alkyl-Ethern aus Lignin
Processing of lignin provides access to mono-aromatic compounds with a styrene-like structure. The vinyl sidechain can be attacked by monooxygenases, such as styrene or indole monooxygenases, to yield enantiopure epoxides. The obtained epoxides can be converted into valuable products, either enzyme- or non-enzyme driven. This provides access to drug-like molecules and technically relevant synthesis precursors. Herein, we report the setup of a simple screening strategy for useful epoxidases.
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