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Neuroscience Bulletin

, Volume 35, Issue 6, pp 1110–1112 | Cite as

Towards the Framework of Understanding Autism Spectrum Disorders

  • Zilong QiuEmail author
  • Bo Yuan
Insight

The prevalence of autism spectrum disorders (ASD) has been high worldwide, reaching 1/59 children in the United States as reported by the Centers of Disease Control and Prevention. Since genetic components play a major role in ASD [1], it is astonishing that the occurrence of ASD would be this high probabily due to genetic causes. It is worthy to note that autistic phenotypes of ASD patients show great diversity. The severity of autistic symptoms may be correlated with whether genetic mutations affect neural development. Thus, we argue that the prevalence of severe ASD may be much lower than the common ASD usually reported. In clinic and neurobiological fields, the ASD candidate genes are usually critical genes whose loss-of-function will affect neural development dramatically. In the following sections, I will focus on the recent progress on clinical diagnosis of severe ASD, as well as genetic and neurobiological studies.

Clinical Diagnosis and Novel Technologies

Clinical diagnosis...

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Copyright information

© Shanghai Institutes for Biological Sciences, CAS 2019

Authors and Affiliations

  1. 1.Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghaiChina

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