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Autonomic Disturbances in Acute Cerebrovascular Disease

  • Jun Mo
  • Lei Huang
  • Jianhua Peng
  • Umut Ocak
  • Jianmin Zhang
  • John H. Zhang
Review
  • 85 Downloads

Abstract

Autonomic disturbances often occur in patients with acute cerebrovascular disease due to damage of the central autonomic network. We summarize the structures of the central autonomic network and the clinical tests used to evaluate the functions of the autonomic nervous system. We review the clinical and experimental findings as well as management strategies of post-stroke autonomic disturbances including electrocardiographic changes, cardiac arrhythmias, myocardial damage, thermoregulatory dysfunction, gastrointestinal dysfunction, urinary incontinence, sexual disorders, and hyperglycemia. The occurrence of autonomic disturbances has been associated with poor outcomes in stroke patients. Autonomic nervous system modulation appears to be an emerging therapeutic strategy for stroke management in addition to treatments for sensorimotor dysfunction.

Keywords

Autonomic disturbance Autonomic nervous system Cerebrovascular disease Stroke 

Notes

Acknowledgements

This review was supported partly by grants from the National Institutes of Health, USA (NS081740 and NS082184).

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Copyright information

© Shanghai Institutes for Biological Sciences, CAS and Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Department of Neurosurgery, The Fourth Affiliated HospitalZhejiang University School of MedicineYiwuChina
  2. 2.Department of Physiology and PharmacologyLoma Linda UniversityLoma LindaUSA
  3. 3.Department of NeurosurgeryLoma Linda UniversityLoma LindaUSA
  4. 4.Department of Neurosurgery, The Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina
  5. 5.Brain Research InstituteZhejiang UniversityHangzhouChina
  6. 6.Collaborative Innovation Center for Brain ScienceZhejiang UniversityHangzhouChina
  7. 7.Department of AnesthesiologyLoma Linda UniversityLoma LindaUSA

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