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Indian Journal of Surgery

, Volume 81, Issue 5, pp 499–501 | Cite as

Bladder Sparing Approach in Carcinosarcoma of Urinary Bladder

  • Shailesh Chandra SahayEmail author
  • Pawan Kesarwani
  • Nikhil Sharma
  • Umar Farouqui
  • Kuldeep Aggarwal
  • Vaseem Shaikh
Case Report
  • 13 Downloads

Abstract

Carcinosarcoma of the bladder is a very rare tumor. This tumor contains both the sarcoma element from mesenchymal lineage and the carcinoma element from epithelial cells. Some investigators feel that these tumors develop as a result of the capability of the undifferentiated, totipotent neoplastic cell to undergo multiple pathways of terminal differentiation into histologically recognizable mesenchymal and epithelial elements. The mesenchymal component may be expressed as a variety of histologic types, including chondrosarcoma, leiomyosarcoma, osteogenic sarcoma, and rhabdomyosarcoma. The epithelial component may be most frequently found in the form of transitional cell carcinoma, adenocarcinoma, or in an admixture of these. Urinary bladder tumor showing cartilaginous and osseous differentiation is very rare. They usually present in advanced stage. Radical cystectomy with chemoradiotherapy is the treatment of choice for urinary bladder carcinosarcoma. We present such a unique case where TURBT combined with radio chemotherapy helped in preserving the bladder with no recurrence until 2 years.

Keywords

Carcinosarcoma TURBT Urinary bladder Mesenchymal tumor Chemotherapy Radiotherapy 

Notes

References

  1. 1.
    Wright JL, Black PC, Brown GA, Porter MP, Kamat AM, Dinney CP, Lin DW (2007) Differences in survival among patients with sarcomatoid carcinoma and urothelial carcinoma of the bladder. J Urol 178:2302–2307CrossRefGoogle Scholar
  2. 2.
    Lopez-Beltran A, Pacelli A, Rothenberg HJ, Wollan PC, Zincke H, Blute ML et al (1998) Carcinosarcoma and sarcomatoid carcinoma of the bladder: clinicopathological study of 41 cases. J Urol 159:1497–1503CrossRefGoogle Scholar
  3. 3.
    Nuwahid F, German K, Campbell F, Stephenson T (1994) Carcinosarcoma in a bladder diverticulum. Urology 44:775–778CrossRefGoogle Scholar
  4. 4.
    Ogishima T, Kawachi Y, Saito A, Suzuki F, Ishi K, Sanata P (2002) Sarcomatoid carcinoma and carcinosarcoma of urinary bladder. Int J Urol 9:354–358CrossRefGoogle Scholar
  5. 5.
    Froehner M, Gaertner HJ, Manseck A, Wirth MP (2001) Durable complete remission of metastatic sarcomatoid carcinoma of the bladder with cisplatin and gemcitabine in an 80-year-old man. Urology 58(5):799CrossRefGoogle Scholar

Copyright information

© Association of Surgeons of India 2019

Authors and Affiliations

  • Shailesh Chandra Sahay
    • 1
    Email author
  • Pawan Kesarwani
    • 1
  • Nikhil Sharma
    • 1
  • Umar Farouqui
    • 1
  • Kuldeep Aggarwal
    • 1
  • Vaseem Shaikh
    • 1
  1. 1.Department of urologyMax Superspeciality hospitalPatparganjIndia

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