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Kaposi sarcoma following autoimmune hemolytic anemia in a patient with chronic lymphocytic leukemia

  • Utku Iltar
  • Vedat Aslan
  • Mesut Gocer
  • Fatma Aykac
  • İlknur Nizam
  • Mehmet Çelik
  • Faruk Gulec
  • Turgay Ulaş
  • Erdal Kurtoğlu
case report
  • 27 Downloads

Summary

Background

Kaposi sarcoma is a low grade angioproliferative disorder which requires infection with human herpes virus 8 for its development. Skin lesions can be observed frequently in chronic lymphocytic leukemia cases, but there is a limited number of cases of Kaposi sarcoma with chronic lymphocytic leukemia in the literature.

Case report

Here, we present a case report of an iatrogenic Kaposi sarcoma in a 79-year-old man recently diagnosed with autoimmune hemolytic anemia secondary to chronic lymphocytic leukemia. After treatment with methylprednisolone and rituximab, the patient developed Kaposi sarcoma nodular lesions on his legs. After three courses of oral etoposide for Kaposi sarcoma, the lesions completely disappeared at the end of the third month of treatment.

Conclusion

Even though the mortality rate is low with Kaposi sarcoma, it can cause physical and psychological burden for the patients. Additional investigations and raising awareness of Kaposi sarcoma while evaluating the differential diagnosis of skin lesions in chronic lymphocytic leukemia are needed. Short-term oral etoposide was tolerated well in this patient with a good clinical response.

Keywords

Kaposi’s sarcoma Chronic lymphocytic leukemia Human herpes virus-8 Rituximab Case report 

Notes

Compliance with ethical guidelines

Conflict of interest

U. Iltar, V. Aslan, M. Gocer, F. Aykac, İ. Nizam, M. Çelik, F. Gulec, T. Ulaş, and E. Kurtoğlu declare that they have no competing interests.

Ethical standards

This article does not contain any studies with human participants or animals performed by any of the authors. For images or other information within the manuscript which identify patients, consent was obtained from them and/or their legal guardians.

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of HematologyAntalya Training and Research HospitalAntalyaTurkey
  2. 2.Department of PathologyAntalya Training and Research HospitalAntalyaTurkey
  3. 3.School of Medicine, Department of Internal Medicine, Division of HematologyNear East UniversityNicosiaCyprus

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