Boosting Global Yellow Fever Vaccine Supply for Epidemic Preparedness: 3 Actions for China and the USA
Yellow fever (YF) is an acute disease caused by a flavivirus that infects the liver. It can cause jaundice, bleeding, kidney damage, and death. No antiviral therapy exists. A vaccine does exist, however, and fortunately confers life-long immunity after a single dose (Monath et al.2016; WHO 2017a, b).
YF is transmitted by mosquitoes in two main cycles. In the sylvatic cycle the virus is spread by forest-dwelling mosquitoes, such as Aedes africanus and Haemagogus mosquitoes, between non-human primates and humans. In the urban cycle the virus is spread primarily by Aedes aegypti mosquitoes between humans. These Aedes mosquitoes can also transmit Dengue, Zika, and Chikungunya viruses.
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Conflict of interest
The authors declare that they have no conflict of interest.
Animal and Human Rights Statement
This article does not contain any studies with human or animal subjects performed by any of the authors.
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