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Virologica Sinica

, Volume 34, Issue 4, pp 347–357 | Cite as

Specific and Selective Bacteriophages in the Fight against Multidrug-resistant Acinetobacter baumannii

  • Natalia Bagińska
  • Anna Pichlak
  • Andrzej Górski
  • Ewa Jończyk-MatysiakEmail author
Review

Abstract

Acinetobacter baumannii causes serious infections especially in immunocompromised and/or hospitalized patients. Several A. baumannii strains are multidrug resistant and infect wounds, bones, and the respiratory tract. Current studies are focused on finding new effective agents against A. baumannii. Phage therapy is a promising means to fight this bacterium and many studies on procuring and applying new phages against A. baumannii are currently being conducted. As shown in animal models, phages against multidrug-resistant A. baumannii may control bacterial infections caused by this pathogen and may be a real hope to solve this dangerous health problem.

Keywords

Acinetobacter baumannii Bacteriophages Phage therapy Multidrug resistance (MDR) 

Notes

Acknowledgements

This work was supported by the statutory funds from the Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences. The authors also thank to Norbert Łodej for making figure to this paper.

Compliance with Ethics Standards

Conflict of interest

Andrzej Górski, is co-inventor of patents owned by the Institute and covering phage preparations. Other authors declare that they have no conflict of interest.

Animal and Human Rights Statement

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Copyright information

© Wuhan Institute of Virology, CAS 2019

Authors and Affiliations

  1. 1.Bacteriophage Laboratory, Hirszfeld Institute of Immunology and Experimental TherapyPolish Academy of SciencesWrocławPoland
  2. 2.Phage Therapy Unit, Hirszfeld Institute of Immunology and Experimental TherapyPolish Academy of SciencesWrocławPoland
  3. 3.Department of Clinical Immunology, Transplantation InstituteMedical University of WarsawWarsawPoland

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