Virologica Sinica

, Volume 32, Issue 3, pp 253–256 | Cite as

Isolation and phylogenetic study of Rift Valley fever virus from the first imported case to China

  • Yongxia Shi
  • Kui Zheng
  • Xiaobo Li
  • Liqiang Li
  • Shufen Li
  • Jinmin Ma
  • Jun Dai
  • Jingkai Ji
  • Shuai Yuan
  • Haorong Lu
  • Jiandong Li
  • Fangfang Sun
  • Xun XuEmail author
  • Jicheng HuangEmail author

Dear Editor,

Rift Valley fever (RVF) is an anthropozoonosis caused by Rift Valley fever virus (RVFV). RVFV belongs to the Phlebovirus genus in the family Bunyaviridae, which is circulating among ruminants. Human infection with RVFV is generally asymptomatic, however, minority of patients develop severe RVF diseases like encephalitis or hemorrhagic complications, with a fatality rate up to 50%. RVF mostly distributed in eastern and southern Africa, including Kenya, Zimbabwe, Zambia, Nambia and Somalia (LaBeaud et al., 2011; Shivanna et al., 2016). Infected cases were also reported in Egypt, Saudi Arabia and Yemen (Ikegami and Makino, 2011). Large outbreaks of RVF occurred in Kenya, Madagascar and South Africa with rapid spread (Jean Jose Nepomichene et al., 2015). In recent years, the import and export trade of animals increased remarkably along with the development of transportation and tourism, which raise the risk of RVFV transmission. The epidemic in Niger caused wide spread...


  1. Barzon L, Pacenti M, Franchin E, et al. 2014. J Clin Microbiol, 52: 3411–3413.CrossRefGoogle Scholar
  2. Bird BH, Khristova ML, Rollin PE, et al. 2007. J Virol, 81: 2805–2816.CrossRefGoogle Scholar
  3. Ikegami T. 2012. Antiviral Res, 95: 293–310.CrossRefGoogle Scholar
  4. Ikegami T, Makino S. 2011. Viruses, 3: 493–519.CrossRefGoogle Scholar
  5. Jean Jose Nepomichene TN, Elissa N, Cardinale E, et al. 2015. J Med Entomol, 52: 962–969.CrossRefGoogle Scholar
  6. LaBeaud AD, Cross PC, Getz WM, et al. 2011. Am J Trop Med Hyg, 84: 641–646.CrossRefGoogle Scholar
  7. Liu W, Sun FJ, Tong YG, et al. 2016. Lancet Infect Dis, 16: 1226.CrossRefGoogle Scholar
  8. Shivanna V, McDowell C, Wilson WC, et al. 2016. Genome Announc, 4: pii: e00926–16.CrossRefGoogle Scholar
  9. Terasaki K, Won S, Makino S. 2013. J Virol, 87: 676–682.CrossRefGoogle Scholar
  10. Wood DE, Salzberg SL. 2014, Genome Biol, 15: R46.CrossRefGoogle Scholar
  11. World Health Organization. 2016. Available: Accessed: 2 August 2016.

Copyright information

© Wuhan Institute of Virology, CAS and Springer Science+Business Media Singapore 2017

Authors and Affiliations

  1. 1.Inspection and Quarantine Technology CenterGuangdong Entry-Exit Inspection and Quarantine BureauGuangzhouChina
  2. 2.BGI-ShenzhenShenzhenChina
  3. 3.Department of BiologyUniversity of CopenhagenCopenhagenDenmark
  4. 4.BGI Education CenterUniversity of Chinese Academy of SciencesShenzhenChina
  5. 5.China National GeneBank-ShenzhenBGI-ShenzhenShenzhenChina

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