Magnetic field gradient inhibits Saccharomyces cerevisiae growth
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The daily exposure of humans to artificial magnetic fields has inspired studies of their effects on biological systems. Different views are advocated by many research groups and few studies have clarified the role of magnetic field gradients in observed results. We investigated the effect of strong gradients and continuous magnetic fields in a cellular system. Colonies of Saccharomyces cerevisiae CCMB 355 were grown in solid and liquid media and exposed to the neodymium–iron–boron magnets. Notably, in solid medium, cells exposed to previously demagnetized NdFeB magnets or to the metals contained in magnets exhibited normal activities, but when exposed to the gradient, growth drastically fails near the magnet, even when the intensity of magnetism was near zero. Increasing the distance of the magnet to regions of weak magnetic field gradient caused decreased cellular malaise. When the magnet was removed, the cells were not capable of growing again, indicating that the gradient killed the exposed cells. In liquid medium, we observed a decrease in the absorbance values in the region of 560 nm when the substrate was directly permeated by a strong magnetic field gradient in comparison with a control without the magnet or with a magnet covered with a thin layer of silicone. This study helps to clarify the effect of the magnetic field gradient in biological systems.
KeywordsNdFeB magnets Magnetobiology Yeast Cell reduction Biocide
We thank the Collection of Cultured Microorganisms of Bahia (CCMB-UEFS) for providing the Saccharomyces cerevisiae cells. We also wish to thank Drª Alice Ferreira da Silva for her assistance with the theoretical work and constructive comments. Maria Gorette Silva do Carmo, Cleidineia Souza de Santana and Pollyana Lopes Valle are acknowledged for their assistance with the practical work.
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
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Conflict of interest
The author(s) declare that they have no conflict of interest
This article does not contain any studies with human participants or animals performed by any of the authors.
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