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International Journal of Hematology

, Volume 108, Issue 6, pp 637–639 | Cite as

Concomitant subcutaneous intravascular lymphoma lesions in a patient with cardiac diffuse large B-cell lymphoma: is intravascular lymphoma a distinct clinical entity?

  • Yoshiaki Abe
  • Yoshiaki Usui
  • Kentaro Narita
  • Masami Takeuchi
  • Kosei Matsue
Case Report

Abstract

We describe a patient who presented with large cardiac diffuse large B-cell lymphoma (DLBCL) and adrenal masses. The patient also had subcutaneous intravascular lymphoma lesions which were detected by random skin biopsy. Although ambiguous, minimal extravascular location of lymphoma cells is permitted for the diagnosis of intravascular large B-cell lymphoma (IVLBCL) in the WHO definition, a number of rare cases have been reported as having concomitant tumours in other organs, such as the adrenal gland, brain, and penis. We assume that IVLBCL might be a peculiar feature of DLBCL characterised by preferential localisation of lymphoma cells within the capillaries rather than a distinct disease entity of DLBCL.

Keywords

Cardiac lymphoma Intravascular large B-cell lymphoma Random skin biopsy 

Notes

Compliance with ethical standards

Conflict of interest

All authors have no conflict of interest.

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Copyright information

© The Japanese Society of Hematology 2018

Authors and Affiliations

  1. 1.Division of Hematology/Oncology, Department of Internal MedicineKameda Medical CenterKamogawa-shiJapan

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