International Journal of Hematology

, Volume 108, Issue 6, pp 647–651 | Cite as

Three cases of spontaneous splenic rupture in malignant lymphoma

  • Jun AmakiEmail author
  • Tatsuya Sekiguchi
  • Shinichiro Hiraiwa
  • Hiroshi Kajiwara
  • Hidetsugu Kawai
  • Akifumi Ichiki
  • Naoya Nakamura
  • Kiyoshi Ando
Case Report


Spontaneous splenic rupture is a rare but often life-threatening condition. However, there is no consensus on appropriate management for this condition, due to its rarity. Here, we report three cases of malignant lymphoma with spontaneous splenic rupture. In each case, progression of splenic bleeding was rapid and complicated by malignant lymphoma. Spontaneous splenic rupture complicated by malignant lymphoma may cause exacerbation of anemia and hypovolemic shock. When splenic rupture is indicated by abdominal pain, tachycardia, or hypotension in a patient with splenomegaly, abdominal examination should be performed immediately, and emergency transcatheter arterial embolization and/or splenectomy should be considered.


Spontaneous splenic rupture Splenomegaly Malignant lymphoma Transcatheter arterial embolization 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.


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Copyright information

© The Japanese Society of Hematology 2018

Authors and Affiliations

  1. 1.Division of Hematology/Oncology, Department of Internal MedicineTokai University School of MedicineIseharaJapan
  2. 2.Department of RadiologyTokai University School of MedicineIseharaJapan
  3. 3.Department of PathologyTokai University School of MedicineIseharaJapan

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